4EML
Synechocystis sp. PCC 6803 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase (MenB) in complex with bicarbonate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
| A | 0009234 | biological_process | menaquinone biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0042372 | biological_process | phylloquinone biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
| B | 0009234 | biological_process | menaquinone biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0042372 | biological_process | phylloquinone biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
| C | 0009234 | biological_process | menaquinone biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0042372 | biological_process | phylloquinone biosynthetic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
| D | 0009234 | biological_process | menaquinone biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0042372 | biological_process | phylloquinone biosynthetic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
| E | 0009234 | biological_process | menaquinone biosynthetic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0042372 | biological_process | phylloquinone biosynthetic process |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
| F | 0009234 | biological_process | menaquinone biosynthetic process |
| F | 0016829 | molecular_function | lyase activity |
| F | 0042372 | biological_process | phylloquinone biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BCT A 301 |
| Chain | Residue |
| A | GLY122 |
| A | GLY123 |
| A | GLN144 |
| A | THR145 |
| A | GLY146 |
| A | TRP174 |
| A | HOH441 |
| A | HOH507 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MPD A 302 |
| Chain | Residue |
| A | VAL197 |
| A | THR61 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 303 |
| Chain | Residue |
| A | ASP198 |
| A | ARG199 |
| A | LEU200 |
| A | GLU201 |
| A | GLU202 |
| A | HOH411 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 304 |
| Chain | Residue |
| A | LYS169 |
| A | GLU172 |
| A | HOH518 |
| A | HOH554 |
| D | ASN192 |
| D | HOH477 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BCT B 301 |
| Chain | Residue |
| B | GLY122 |
| B | GLY123 |
| B | GLN144 |
| B | THR145 |
| B | GLY146 |
| B | TRP174 |
| B | HOH426 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 302 |
| Chain | Residue |
| B | THR61 |
| B | GLY62 |
| B | GLU201 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 303 |
| Chain | Residue |
| B | SER269 |
| B | GLN270 |
| B | TYR271 |
| B | PRO272 |
| B | TRP273 |
| C | ASN53 |
| C | ARG54 |
| C | HOH470 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BCT C 301 |
| Chain | Residue |
| C | GLY122 |
| C | GLY123 |
| C | GLN144 |
| C | THR145 |
| C | GLY146 |
| C | TRP174 |
| C | HOH429 |
| C | HOH441 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 302 |
| Chain | Residue |
| C | PHE152 |
| C | ASP153 |
| C | SO4303 |
| C | HOH407 |
| C | HOH429 |
| C | HOH460 |
| E | TYR248 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 303 |
| Chain | Residue |
| C | ASN97 |
| C | GOL302 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 304 |
| Chain | Residue |
| C | THR61 |
| C | LEU115 |
| C | LEU200 |
| C | GLU201 |
| C | HOH519 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BCT D 301 |
| Chain | Residue |
| D | GLY122 |
| D | GLY123 |
| D | GLN144 |
| D | THR145 |
| D | GLY146 |
| D | TRP174 |
| D | HOH415 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 302 |
| Chain | Residue |
| D | THR61 |
| D | GLY62 |
| D | ALA63 |
| D | GLY64 |
| D | HOH513 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BCT E 301 |
| Chain | Residue |
| E | GLY122 |
| E | GLY123 |
| E | GLN144 |
| E | THR145 |
| E | GLY146 |
| E | TRP174 |
| E | HOH441 |
| E | HOH506 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD E 302 |
| Chain | Residue |
| E | THR61 |
| E | GLY62 |
| E | LEU115 |
| E | VAL197 |
| E | GLU201 |
| E | HOH462 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL E 304 |
| Chain | Residue |
| E | GLN270 |
| E | TYR271 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BCT F 301 |
| Chain | Residue |
| F | GLY122 |
| F | GLY123 |
| F | GLN144 |
| F | THR145 |
| F | GLY146 |
| F | TRP174 |
| F | HOH445 |
| F | HOH501 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD F 302 |
| Chain | Residue |
| F | GLY62 |
| F | TYR71 |
| F | LEU115 |
| F | HOH505 |
| F | HOH550 |
| F | THR61 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL F 303 |
| Chain | Residue |
| F | GLN179 |
| F | TYR180 |
| F | SER181 |
| F | HOH557 |
Functional Information from PROSITE/UniProt
| site_id | PS00166 |
| Number of Residues | 21 |
| Details | ENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. IAlVAGyaiGGGhvlhLvCDL |
| Chain | Residue | Details |
| A | ILE113-LEU133 |
