Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

4EMD

Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to CMP and SO4

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0005524molecular_functionATP binding
A0008299biological_processisoprenoid biosynthetic process
A0016114biological_processterpenoid biosynthetic process
A0016301molecular_functionkinase activity
A0016740molecular_functiontransferase activity
A0019288biological_processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
A0050515molecular_function4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE C5P A 401
ChainResidue
ATYR36
AHOH598
AHOH680
AHOH709
AHOH789
AHIS37
ALEU39
ASER147
AARG163
ATHR189
APRO190
APHE193
AHOH545

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE SO4 A 402
ChainResidue
AVAL107
AALA108
AALA112
AGLY113
AGLY114
AHOH529
AHOH544
AHOH559
AHOH579
AHOH608
AHOH657
AHOH791
AHOH792

237735

PDB entries from 2025-06-18

PDB statisticsPDBj update infoContact PDBjnumon