4EMB
Crystal structure of a phosphoglycerate mutase gpmA from Borrelia burgdorferi B31
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004619 | molecular_function | phosphoglycerate mutase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016868 | molecular_function | intramolecular phosphotransferase activity |
| A | 0046538 | molecular_function | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004619 | molecular_function | phosphoglycerate mutase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016868 | molecular_function | intramolecular phosphotransferase activity |
| B | 0046538 | molecular_function | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004619 | molecular_function | phosphoglycerate mutase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006094 | biological_process | gluconeogenesis |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0016868 | molecular_function | intramolecular phosphotransferase activity |
| C | 0046538 | molecular_function | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004619 | molecular_function | phosphoglycerate mutase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006094 | biological_process | gluconeogenesis |
| D | 0006096 | biological_process | glycolytic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0016868 | molecular_function | intramolecular phosphotransferase activity |
| D | 0046538 | molecular_function | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 301 |
| Chain | Residue |
| A | LEU24 |
| A | PHE25 |
| A | THR26 |
| A | GLY27 |
| A | GLU92 |
| A | TYR95 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 301 |
| Chain | Residue |
| B | GLU92 |
| B | TYR95 |
| B | PHE25 |
| B | THR26 |
| B | GLY27 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 301 |
| Chain | Residue |
| C | LEU24 |
| C | PHE25 |
| C | THR26 |
| C | GLY27 |
| C | GLU92 |
| C | TYR95 |
Functional Information from PROSITE/UniProt
| site_id | PS00175 |
| Number of Residues | 10 |
| Details | PG_MUTASE Phosphoglycerate mutase family phosphohistidine signature. LvRHGEsEwN |
| Chain | Residue | Details |
| A | LEU11-ASN20 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Tele-phosphohistidine intermediate => ECO:0000255|HAMAP-Rule:MF_01039 |
| Chain | Residue | Details |
| A | HIS14 | |
| B | HIS14 | |
| C | HIS14 | |
| D | HIS14 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_01039 |
| Chain | Residue | Details |
| A | GLU92 | |
| B | GLU92 | |
| C | GLU92 | |
| D | GLU92 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 28 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01039 |
| Chain | Residue | Details |
| B | THR26 | |
| B | ARG65 | |
| B | GLU92 | |
| B | LYS103 | |
| B | ARG119 | |
| B | GLY188 | |
| C | ARG13 | |
| C | THR26 | |
| C | ARG65 | |
| C | GLU92 | |
| C | LYS103 | |
| C | ARG119 | |
| C | GLY188 | |
| D | ARG13 | |
| D | THR26 | |
| D | ARG65 | |
| D | GLU92 | |
| D | LYS103 | |
| D | ARG119 | |
| D | GLY188 | |
| A | ARG13 | |
| A | THR26 | |
| A | ARG65 | |
| A | GLU92 | |
| A | LYS103 | |
| A | ARG119 | |
| A | GLY188 | |
| B | ARG13 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_01039 |
| Chain | Residue | Details |
| A | HIS187 | |
| B | HIS187 | |
| C | HIS187 | |
| D | HIS187 |
