4EG1
Trypanosoma brucei methionyl-tRNA synthetase in complex with substrate Methionine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004825 | molecular_function | methionine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006431 | biological_process | methionyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004825 | molecular_function | methionine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006431 | biological_process | methionyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 801 |
| Chain | Residue |
| A | ARG271 |
| A | VAL275 |
| A | SER714 |
| A | PRO718 |
| A | VAL722 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 802 |
| Chain | Residue |
| A | ARG719 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 803 |
| Chain | Residue |
| A | ARG583 |
| A | ARG601 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 804 |
| Chain | Residue |
| A | VAL396 |
| A | HOH1017 |
| A | HIS395 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 805 |
| Chain | Residue |
| A | LYS276 |
| A | ILE738 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 806 |
| Chain | Residue |
| A | GLU732 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 807 |
| Chain | Residue |
| A | HIS289 |
| A | LYS338 |
| A | ASN458 |
| A | TRP459 |
| A | ALA460 |
| A | CAS470 |
| B | ASN458 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MET A 808 |
| Chain | Residue |
| A | ILE248 |
| A | TYR249 |
| A | TYR250 |
| A | ASP287 |
| A | TRP474 |
| A | ALA477 |
| A | ASN480 |
| A | TYR481 |
| A | ILE519 |
| A | HIS523 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 801 |
| Chain | Residue |
| B | ASP500 |
| B | PHE502 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 802 |
| Chain | Residue |
| B | ARG583 |
| B | ARG601 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 803 |
| Chain | Residue |
| B | TYR579 |
| B | ARG583 |
| B | GLU605 |
| B | ILE665 |
| B | ILE666 |
| B | PHE669 |
| B | ARG673 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL B 804 |
| Chain | Residue |
| B | HOH1035 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 805 |
| Chain | Residue |
| B | HIS289 |
| B | THR333 |
| B | LYS338 |
| B | TRP459 |
| B | ALA460 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MET B 806 |
| Chain | Residue |
| B | ILE248 |
| B | TYR250 |
| B | ASP287 |
| B | TRP474 |
| B | ALA477 |
| B | LEU478 |
| B | TYR481 |
| B | ILE519 |
| B | HIS523 |
