4EEC
Crystal Structure of the glycopeptide antibiotic sulfotransferase StaL complexed with A3P and desulfo-A47934.
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0008146 | molecular_function | sulfotransferase activity |
A | 0016740 | molecular_function | transferase activity |
A | 0017000 | biological_process | antibiotic biosynthetic process |
A | 0051923 | biological_process | sulfation |
B | 0005737 | cellular_component | cytoplasm |
B | 0008146 | molecular_function | sulfotransferase activity |
B | 0016740 | molecular_function | transferase activity |
B | 0017000 | biological_process | antibiotic biosynthetic process |
B | 0051923 | biological_process | sulfation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE 0UZ C 405 |
Chain | Residue |
A | LYS103 |
A | ARG130 |
C | GHP404 |
C | OMY406 |
C | 3FG407 |
site_id | AC2 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE A3P A 301 |
Chain | Residue |
A | HIS16 |
A | TRP17 |
A | ARG90 |
A | SER98 |
A | ARG101 |
A | TYR163 |
A | CYS196 |
A | THR197 |
A | LEU198 |
A | MET201 |
A | LYS12 |
A | ALA13 |
A | GLY14 |
A | GLY15 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P49891, ECO:0000305|PubMed:17329243 |
Chain | Residue | Details |
A | HIS67 | |
B | HIS67 |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000305|PubMed:17329243, ECO:0000305|PubMed:22753479 |
Chain | Residue | Details |
A | LYS12 | |
A | ARG90 | |
A | SER98 | |
A | TYR163 | |
B | LYS12 | |
B | ARG90 | |
B | SER98 | |
B | TYR163 |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000305|PubMed:22753479 |
Chain | Residue | Details |
A | HIS43 | |
A | TRP132 | |
A | CYS196 | |
B | HIS43 | |
B | TRP132 | |
B | CYS196 |