4ED4
Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016114 | biological_process | terpenoid biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019288 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| A | 0050515 | molecular_function | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE ATP A 401 |
| Chain | Residue |
| A | PRO73 |
| A | MET111 |
| A | ALA112 |
| A | GLY113 |
| A | GLY114 |
| A | ASP117 |
| A | ASP148 |
| A | THR189 |
| A | HOH508 |
| A | HOH514 |
| A | HOH516 |
| A | ARG77 |
| A | HOH518 |
| A | HOH520 |
| A | HOH536 |
| A | HOH560 |
| A | HOH568 |
| A | HOH574 |
| A | HOH623 |
| A | HOH655 |
| A | HOH683 |
| A | ASN78 |
| A | LEU79 |
| A | LYS103 |
| A | VAL107 |
| A | ALA108 |
| A | GLY109 |
| A | GLY110 |
