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4ECX

Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 300 sec

Functional Information from GO Data
ChainGOidnamespacecontents
A0003684molecular_functiondamaged DNA binding
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE MG A 501
ChainResidue
AASP13
AASP115
AGLU116
ACA502
AMG503
AHOH603
PDT8
PDA9
PDTP504

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE CA A 502
ChainResidue
AASP13
AMET14
AASP115
AMG501
PDA9
PDTP504
PDPO505

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG A 503
ChainResidue
AASP13
AMET14
AASP115
AMG501
PDA9
PDTP504
PDPO505

site_idAC4
Number of Residues30
DetailsBINDING SITE FOR RESIDUE DTP P 504
ChainResidue
AASP13
AMET14
AASP15
ACYS16
APHE17
APHE18
AILE48
AALA49
ATYR52
AARG55
AARG61
AASP115
ALYS231
AMG501
ACA502
AMG503
AHOH601
AHOH602
AHOH603
AHOH638
AHOH665
AHOH733
AHOH888
AHOH943
AHOH994
PDT8
PHOH207
TDT3
TDT4
TDA5

site_idAC5
Number of Residues19
DetailsBINDING SITE FOR RESIDUE DPO P 505
ChainResidue
AASP13
AMET14
AASP15
ACYS16
APHE17
ATYR52
AARG55
AARG61
AASP115
ALYS231
ACA502
AMG503
AHOH601
AHOH638
AHOH665
AHOH888
AHOH994
PDA9
PMG506

site_idAC6
Number of Residues10
DetailsBINDING SITE FOR RESIDUE GOL A 506
ChainResidue
AARG24
AGLN25
APRO244
ASER248
AGLY276
AGLU277
AHOH610
AHOH634
AHOH691
AHOH716

site_idAC7
Number of Residues11
DetailsBINDING SITE FOR RESIDUE GOL A 507
ChainResidue
AASN26
APRO27
AHIS28
AGLY271
AGLU273
ATYR274
AGLU277
AHOH806
AHOH819
AHOH898
AHOH964

site_idAC8
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG P 506
ChainResidue
PDPO505
AARG61
AHOH602
AHOH665
AHOH888
AHOH943
PDA9

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO
ChainResidueDetails
AASP13
AMET14
AASP115
AGLU116

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197
ChainResidueDetails
AARG61

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PDB entries from 2024-11-06

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