4ECU

Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 200 sec

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	CA502
A	MG503
A	HOH604
P	DT8
P	DA9
P	DTP504

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 502

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG501
P	DA9
P	DTP504
P	DPO505

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG501
P	DA9
P	DTP504
P	DPO505

---

site_id	AC4
Number of Residues	29
Details	BINDING SITE FOR RESIDUE DTP P 504

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	MG501
A	CA502
A	MG503
A	HOH601
A	HOH602
A	HOH604
A	HOH617
A	HOH644
A	HOH754
A	HOH843
A	HOH861
P	DT8
P	HOH208
T	DT3
T	DT4
T	DA5

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE DPO P 505

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	CA502
A	MG503
A	HOH617
A	HOH644
A	HOH843
A	HOH861
P	DA9
P	MG506

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 507

Chain	Residue
A	ARG24
A	PRO244
A	PHE247
A	SER248
A	GLY276
A	GLU277
A	HOH609
A	HOH655
A	HOH658
A	HOH798

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 508

Chain	Residue
A	ASN26
A	PRO27
A	HIS28
A	GLY271
A	GLU273
A	TYR274
A	GLU277
A	HOH844
A	HOH855

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG P 506

Chain	Residue
A	ARG61
A	HOH601
A	HOH644
A	HOH843
P	DA9
P	DPO505

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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