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4EC7

Cobra NGF in complex with lipid

Functional Information from GO Data
ChainGOidnamespacecontents
A0005102molecular_functionsignaling receptor binding
A0005576cellular_componentextracellular region
A0007165biological_processsignal transduction
A0008083molecular_functiongrowth factor activity
A0008191molecular_functionmetalloendopeptidase inhibitor activity
A0008289molecular_functionlipid binding
A0030414molecular_functionpeptidase inhibitor activity
A0035821biological_processmodulation of process of another organism
A0090729molecular_functiontoxin activity
B0005102molecular_functionsignaling receptor binding
B0005576cellular_componentextracellular region
B0007165biological_processsignal transduction
B0008083molecular_functiongrowth factor activity
B0008191molecular_functionmetalloendopeptidase inhibitor activity
B0008289molecular_functionlipid binding
B0030414molecular_functionpeptidase inhibitor activity
B0035821biological_processmodulation of process of another organism
B0090729molecular_functiontoxin activity
Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE L44 A 200
ChainResidue
ALEU42
APHE99
AHOH302
AHOH308
BGLU10
BTRP20
BTYR47
BTYR50
BLYS86
BTRP97
ATYR47
ALYS48
AGLU49
ATYR50
ATYR77
ATHR79
ALYS86
ATRP97

Functional Information from PROSITE/UniProt
site_idPS00248
Number of Residues14
DetailsNGF_1 Nerve growth factor family signature. GCRGIDsshWnSyC
ChainResidueDetails
AGLY65-CYS78

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:22649032, ECO:0007744|PDB:4EC7
ChainResidueDetails
ALYS86
BLYS86

222415

PDB entries from 2024-07-10

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