4EB7

A. fulgidus IscS-IscU complex structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0016226	biological_process	iron-sulfur cluster assembly
A	0016740	molecular_function	transferase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031071	molecular_function	cysteine desulfurase activity
A	0044571	biological_process	[2Fe-2S] cluster assembly
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0005737	cellular_component	cytoplasm
B	0016226	biological_process	iron-sulfur cluster assembly
B	0016740	molecular_function	transferase activity
B	0030170	molecular_function	pyridoxal phosphate binding
B	0031071	molecular_function	cysteine desulfurase activity
B	0044571	biological_process	[2Fe-2S] cluster assembly
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	0005506	molecular_function	iron ion binding
C	0016226	biological_process	iron-sulfur cluster assembly
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PLP A 401

Chain	Residue
A	THR70
A	HIS98
A	ASN149
A	ASP173
A	THR175
A	HOH516
B	GLY233
B	SER234

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 402

Chain	Residue
A	GLY179
A	ILE181
A	GLU182
A	VAL183
A	TRP254
A	EPE404
A	LEU55

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 403

Chain	Residue
A	ILE78
A	GLN218
A	PRO219
A	VAL220
B	ILE78
B	PHE107

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EPE A 404

Chain	Residue
A	LYS54
A	ASN57
A	GLN109
A	GLY112
A	PHE113
A	GLU114
A	VAL115
A	ALA251
A	GOL402

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PLP B 401

Chain	Residue
A	SER234
B	ALA69
B	THR70
B	HIS98
B	ASN149
B	ASP173
B	THR175
B	HOH504

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 402

Chain	Residue
B	THR66
B	SER67
B	GLY205
B	ARG231
B	GLU235
B	ASN236

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FES C 201

Chain	Residue
A	CYS321
C	CYS33
C	ASP35
C	CYS58
C	HIS101
C	CYS102
C	FES202

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FES C 202

Chain	Residue
A	CYS321
C	GLY34
C	ASP35
C	CYS58
C	FES201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Cysteine persulfide intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_00331","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23160436","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00331","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22511353","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23160436","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00331","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22511353","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"description":"via persulfide group","evidences":[{"source":"HAMAP-Rule","id":"MF_00331","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22511353","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PDB","id":"4EB5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---