4EAX

Mouse NGF in complex with Lyso-PS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005102	molecular_function	signaling receptor binding
B	0005102	molecular_function	signaling receptor binding
C	0005102	molecular_function	signaling receptor binding
D	0005102	molecular_function	signaling receptor binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE S12 B 201

Chain	Residue
A	ASN45
B	TRP99
B	HOH304
A	LYS88
A	TRP99
B	ASN45
B	VAL48
B	PHE49
B	ARG50
B	TYR52
B	LYS88

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE S12 D 201

Chain	Residue
B	GLY10
C	LYS88
C	TRP99
D	ILE44
D	ASN45
D	VAL48
D	PHE49
D	ARG50
D	LYS88
D	TRP99
D	HOH307

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Functional Information from PROSITE/UniProt

site_id	PS00248
Number of Residues	14
Details	NGF_1 Nerve growth factor family signature. GCRGIDskhWnSyC

Chain	Residue	Details
A	GLY67-CYS80

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: in other chain => ECO:0000269|PubMed:22649032, ECO:0007744|PDB:4EAX

Chain	Residue	Details
A	ARG50
B	ARG50
C	ARG50
D	ARG50

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: in other chain => ECO:0000269|PubMed:26144237, ECO:0007744|PDB:4XPJ

Chain	Residue	Details
A	TYR52
B	TYR52
C	TYR52
D	TYR52

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:22649032, ECO:0007744|PDB:4EAX

Chain	Residue	Details
A	LYS88
B	LYS88
C	LYS88
D	LYS88

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