4E51

Crystal structure of a histidyl-tRNA synthetase HisRS from Burkholderia thailandensis bound to histidine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004821	molecular_function	histidine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006427	biological_process	histidyl-tRNA aminoacylation
A	0016874	molecular_function	ligase activity
A	0140101	molecular_function	catalytic activity, acting on a tRNA
B	0000166	molecular_function	nucleotide binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004821	molecular_function	histidine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006412	biological_process	translation
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006427	biological_process	histidyl-tRNA aminoacylation
B	0016874	molecular_function	ligase activity
B	0140101	molecular_function	catalytic activity, acting on a tRNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HIS A 501

Chain	Residue
A	GLU90
A	GLY310
A	TRP311
A	THR92
A	ARG120
A	GLN134
A	GLU138
A	ARG265
A	TYR269
A	TYR270
A	TYR294

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE HIS B 501

Chain	Residue
B	GLU90
B	THR92
B	GLN134
B	GLU138
B	TYR269
B	TYR270
B	TYR294
B	GLY310
B	TRP311

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