4E4S

Crystal structure of Pika GITRL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002309	biological_process	T cell proliferation involved in immune response
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
A	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
A	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B	0002309	biological_process	T cell proliferation involved in immune response
B	0005164	molecular_function	tumor necrosis factor receptor binding
B	0006955	biological_process	immune response
B	0016020	cellular_component	membrane
B	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
B	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
C	0002309	biological_process	T cell proliferation involved in immune response
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0006955	biological_process	immune response
C	0016020	cellular_component	membrane
C	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
C	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
D	0002309	biological_process	T cell proliferation involved in immune response
D	0005164	molecular_function	tumor necrosis factor receptor binding
D	0006955	biological_process	immune response
D	0016020	cellular_component	membrane
D	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
D	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
E	0002309	biological_process	T cell proliferation involved in immune response
E	0005164	molecular_function	tumor necrosis factor receptor binding
E	0006955	biological_process	immune response
E	0016020	cellular_component	membrane
E	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
E	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
F	0002309	biological_process	T cell proliferation involved in immune response
F	0005164	molecular_function	tumor necrosis factor receptor binding
F	0006955	biological_process	immune response
F	0016020	cellular_component	membrane
F	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
F	0033209	biological_process	tumor necrosis factor-mediated signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 201

Chain	Residue
A	LEU42
A	GLU89
B	LYS9
B	TYR46
F	PHE58

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL B 201

Chain	Residue
C	GLN122
B	ARG36
B	GLY93
B	ASP94
C	ASN40

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 201

Chain	Residue
C	GLY47
C	ARG48
C	ILE81
C	ASN83
C	HOH340

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 202

Chain	Residue
C	SER31
C	ASP32
C	TRP33
C	GLU97
C	HOH314

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL D 201

Chain	Residue
C	LYS67
C	TYR88
C	GLU89
C	HOH326
D	ARG48
D	ASN83
D	TYR112

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL E 201

Chain	Residue
E	ASN52
E	TYR55
E	SER78

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL E 202

Chain	Residue
E	LYS3

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site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL F 201

Chain	Residue
B	LYS67
B	TYR88
B	GLU89
F	GLY47
F	ARG48
F	ASN83
F	TYR112
F	HOH318

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site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 202

Chain	Residue
B	ASP104
F	GLU16
F	ASP32

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