4E4G

Crystal structure of putative Methylmalonate-semialdehyde dehydrogenase from Sinorhizobium meliloti 1021

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004491	molecular_function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
A	0006210	biological_process	thymine catabolic process
A	0006574	biological_process	L-valine catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0000166	molecular_function	nucleotide binding
B	0004491	molecular_function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
B	0006210	biological_process	thymine catabolic process
B	0006574	biological_process	L-valine catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0000166	molecular_function	nucleotide binding
C	0004491	molecular_function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
C	0006210	biological_process	thymine catabolic process
C	0006574	biological_process	L-valine catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0000166	molecular_function	nucleotide binding
D	0004491	molecular_function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
D	0006210	biological_process	thymine catabolic process
D	0006574	biological_process	L-valine catabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
E	0000166	molecular_function	nucleotide binding
E	0004491	molecular_function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
E	0006210	biological_process	thymine catabolic process
E	0006574	biological_process	L-valine catabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
F	0000166	molecular_function	nucleotide binding
F	0004491	molecular_function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
F	0006210	biological_process	thymine catabolic process
F	0006574	biological_process	L-valine catabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
G	0000166	molecular_function	nucleotide binding
G	0004491	molecular_function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
G	0006210	biological_process	thymine catabolic process
G	0006574	biological_process	L-valine catabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
H	0000166	molecular_function	nucleotide binding
H	0004491	molecular_function	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
H	0006210	biological_process	thymine catabolic process
H	0006574	biological_process	L-valine catabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

Functional Information from PROSITE/UniProt

site_id	PS00070
Number of Residues	12
Details	ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. YgSAGERCMAIS

Chain	Residue	Details
A	TYR272-SER283

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