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4E21

The crystal structure of 6-phosphogluconate dehydrogenase from Geobacter metallireducens

Functional Information from GO Data
ChainGOidnamespacecontents
A0004616molecular_functionphosphogluconate dehydrogenase (decarboxylating) activity
A0006098biological_processpentose-phosphate shunt
A0016491molecular_functionoxidoreductase activity
A0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A0050661molecular_functionNADP binding
B0004616molecular_functionphosphogluconate dehydrogenase (decarboxylating) activity
B0006098biological_processpentose-phosphate shunt
B0016491molecular_functionoxidoreductase activity
B0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B0050661molecular_functionNADP binding
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE MRD A 401
ChainResidue
AGLU195
BPHE329
ATYR196
AASP280
ASER281
AARG308
AHOH544
AHOH584
AHOH587
BARG326

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MRD B 401
ChainResidue
AARG326
BGLU195
BTYR196
BSER281
BARG308
BHOH534
BHOH588

Functional Information from PROSITE/UniProt
site_idPS00895
Number of Residues14
Details3_HYDROXYISOBUT_DH 3-hydroxyisobutyrate dehydrogenase signature. MIGLGrMGadMVrR
ChainResidueDetails
AMSE5-ARG18

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PDB entries from 2026-09-30

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