4E0T
Crystal structure of CdpNPT in its unbound state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004177 | molecular_function | aminopeptidase activity |
| B | 0004659 | molecular_function | prenyltransferase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0009820 | biological_process | alkaloid metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004177 | molecular_function | aminopeptidase activity |
| C | 0004659 | molecular_function | prenyltransferase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0009820 | biological_process | alkaloid metabolic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004177 | molecular_function | aminopeptidase activity |
| D | 0004659 | molecular_function | prenyltransferase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0009820 | biological_process | alkaloid metabolic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 601 |
| Chain | Residue |
| A | TYR137 |
| A | GLN138 |
| D | LEU47 |
| D | LEU48 |
| D | PHE49 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 602 |
| Chain | Residue |
| D | GLN138 |
| D | HIS143 |
| A | LEU47 |
| A | LEU48 |
| A | PHE49 |
| D | TYR137 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 603 |
| Chain | Residue |
| A | THR108 |
| A | PHE223 |
| A | HOH770 |
| A | HOH925 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 605 |
| Chain | Residue |
| A | HIS143 |
| A | HOH736 |
| D | TYR55 |
| D | HIS59 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 606 |
| Chain | Residue |
| A | LYS364 |
| A | SER421 |
| A | TYR431 |
| A | SER433 |
| A | TYR435 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 607 |
| Chain | Residue |
| A | ASP279 |
| A | PRO280 |
| A | ALA281 |
| C | ARG185 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 608 |
| Chain | Residue |
| A | GLN159 |
| A | ASN166 |
| A | ILE167 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 609 |
| Chain | Residue |
| A | LEU369 |
| A | ILE372 |
| A | GLU374 |
| A | ILE377 |
| A | THR414 |
| A | GLN417 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 610 |
| Chain | Residue |
| A | ILE38 |
| A | THR42 |
| A | LYS45 |
| A | HOH873 |
| B | GLN78 |
| B | GLU81 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 501 |
| Chain | Residue |
| A | GLN88 |
| B | LEU48 |
| B | GLN88 |
| B | HOH633 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 502 |
| Chain | Residue |
| A | GLU81 |
| B | THR42 |
| B | LYS45 |
| B | HOH625 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 503 |
| Chain | Residue |
| B | TYR137 |
| B | GLN138 |
| C | LEU47 |
| C | LEU48 |
| C | PHE49 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 504 |
| Chain | Residue |
| B | ARG129 |
| B | EDO509 |
| B | HOH611 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 505 |
| Chain | Residue |
| B | ASN120 |
| B | LYS364 |
| B | SER421 |
| B | TYR431 |
| B | SER433 |
| B | TYR435 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 506 |
| Chain | Residue |
| B | ASP279 |
| B | PRO280 |
| B | ALA281 |
| B | HOH676 |
| D | ARG185 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 507 |
| Chain | Residue |
| B | GLN159 |
| B | ASN166 |
| B | ILE167 |
| B | HOH713 |
| B | HOH741 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 508 |
| Chain | Residue |
| B | LEU369 |
| B | ILE372 |
| B | GLU374 |
| B | ILE377 |
| B | THR414 |
| B | GLN417 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 509 |
| Chain | Residue |
| B | GLU116 |
| B | TYR366 |
| B | TYR435 |
| B | EDO504 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 701 |
| Chain | Residue |
| A | ARG185 |
| C | ASP279 |
| C | PRO280 |
| C | ALA281 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 702 |
| Chain | Residue |
| C | GLN88 |
| C | LEU89 |
| C | PRO92 |
| C | GLN157 |
| C | HOH872 |
| C | HOH894 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 703 |
| Chain | Residue |
| C | HOH826 |
| D | GLN88 |
| C | LEU48 |
| C | ALA87 |
| C | GLN88 |
| C | EDO709 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 704 |
| Chain | Residue |
| B | LEU47 |
| B | LEU48 |
| B | PHE49 |
| C | TYR137 |
| C | GLN138 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 705 |
| Chain | Residue |
| C | ARG129 |
| C | ALA131 |
| C | HOH941 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL C 706 |
| Chain | Residue |
| C | ASN120 |
| C | LYS364 |
| C | SER421 |
| C | TYR431 |
| C | SER433 |
| C | TYR435 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 707 |
| Chain | Residue |
| C | GLN159 |
| C | ASN166 |
| C | ILE167 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 708 |
| Chain | Residue |
| C | LEU369 |
| C | ILE372 |
| C | GLU374 |
| C | ILE377 |
| C | THR414 |
| C | GLN417 |
| site_id | CC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 709 |
| Chain | Residue |
| C | GLN88 |
| C | EDO703 |
| D | LEU48 |
| D | PHE49 |
| D | ALA87 |
| D | GLN88 |
| D | HOH745 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 710 |
| Chain | Residue |
| C | THR42 |
| C | LYS45 |
| D | GLU81 |
| site_id | DC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 501 |
| Chain | Residue |
| D | GLU116 |
| D | MET349 |
| D | HOH682 |
| D | HOH699 |
| site_id | DC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 502 |
| Chain | Residue |
| D | SER99 |
| D | ARG102 |
| site_id | DC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 503 |
| Chain | Residue |
| D | GLN159 |
| D | ASN166 |
| D | ILE167 |
| D | HOH810 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL D 504 |
| Chain | Residue |
| D | ASN120 |
| D | LYS364 |
| D | SER421 |
| D | TYR431 |
| D | SER433 |
| D | TYR435 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 505 |
| Chain | Residue |
| B | ARG185 |
| D | ASP279 |
| D | PRO280 |
| D | ALA281 |
| D | HOH769 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 506 |
| Chain | Residue |
| D | LEU369 |
| D | ILE372 |
| D | GLU374 |
| D | ILE377 |
| D | THR414 |
| D | GLN417 |
| site_id | DC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 507 |
| Chain | Residue |
| C | GLN78 |
| C | GLU81 |
| D | THR42 |
| D | LYS45 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22683356","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4E0U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q4WAW7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
