4E0T
Crystal structure of CdpNPT in its unbound state
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004177 | molecular_function | aminopeptidase activity |
A | 0004659 | molecular_function | prenyltransferase activity |
A | 0006508 | biological_process | proteolysis |
A | 0009820 | biological_process | alkaloid metabolic process |
A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
B | 0004177 | molecular_function | aminopeptidase activity |
B | 0004659 | molecular_function | prenyltransferase activity |
B | 0006508 | biological_process | proteolysis |
B | 0009820 | biological_process | alkaloid metabolic process |
B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
C | 0004177 | molecular_function | aminopeptidase activity |
C | 0004659 | molecular_function | prenyltransferase activity |
C | 0006508 | biological_process | proteolysis |
C | 0009820 | biological_process | alkaloid metabolic process |
C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
D | 0004177 | molecular_function | aminopeptidase activity |
D | 0004659 | molecular_function | prenyltransferase activity |
D | 0006508 | biological_process | proteolysis |
D | 0009820 | biological_process | alkaloid metabolic process |
D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 601 |
Chain | Residue |
A | TYR137 |
A | GLN138 |
D | LEU47 |
D | LEU48 |
D | PHE49 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 602 |
Chain | Residue |
D | GLN138 |
D | HIS143 |
A | LEU47 |
A | LEU48 |
A | PHE49 |
D | TYR137 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 603 |
Chain | Residue |
A | THR108 |
A | PHE223 |
A | HOH770 |
A | HOH925 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE PEG A 605 |
Chain | Residue |
A | HIS143 |
A | HOH736 |
D | TYR55 |
D | HIS59 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL A 606 |
Chain | Residue |
A | LYS364 |
A | SER421 |
A | TYR431 |
A | SER433 |
A | TYR435 |
site_id | AC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 607 |
Chain | Residue |
A | ASP279 |
A | PRO280 |
A | ALA281 |
C | ARG185 |
site_id | AC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 608 |
Chain | Residue |
A | GLN159 |
A | ASN166 |
A | ILE167 |
site_id | AC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA A 609 |
Chain | Residue |
A | LEU369 |
A | ILE372 |
A | GLU374 |
A | ILE377 |
A | THR414 |
A | GLN417 |
site_id | AC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 610 |
Chain | Residue |
A | ILE38 |
A | THR42 |
A | LYS45 |
A | HOH873 |
B | GLN78 |
B | GLU81 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 501 |
Chain | Residue |
A | GLN88 |
B | LEU48 |
B | GLN88 |
B | HOH633 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 502 |
Chain | Residue |
A | GLU81 |
B | THR42 |
B | LYS45 |
B | HOH625 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 503 |
Chain | Residue |
B | TYR137 |
B | GLN138 |
C | LEU47 |
C | LEU48 |
C | PHE49 |
site_id | BC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 504 |
Chain | Residue |
B | ARG129 |
B | EDO509 |
B | HOH611 |
site_id | BC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CL B 505 |
Chain | Residue |
B | ASN120 |
B | LYS364 |
B | SER421 |
B | TYR431 |
B | SER433 |
B | TYR435 |
site_id | BC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL B 506 |
Chain | Residue |
B | ASP279 |
B | PRO280 |
B | ALA281 |
B | HOH676 |
D | ARG185 |
site_id | BC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL B 507 |
Chain | Residue |
B | GLN159 |
B | ASN166 |
B | ILE167 |
B | HOH713 |
B | HOH741 |
site_id | BC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA B 508 |
Chain | Residue |
B | LEU369 |
B | ILE372 |
B | GLU374 |
B | ILE377 |
B | THR414 |
B | GLN417 |
site_id | BC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 509 |
Chain | Residue |
B | GLU116 |
B | TYR366 |
B | TYR435 |
B | EDO504 |
site_id | CC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL C 701 |
Chain | Residue |
A | ARG185 |
C | ASP279 |
C | PRO280 |
C | ALA281 |
site_id | CC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO C 702 |
Chain | Residue |
C | GLN88 |
C | LEU89 |
C | PRO92 |
C | GLN157 |
C | HOH872 |
C | HOH894 |
site_id | CC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO C 703 |
Chain | Residue |
C | HOH826 |
D | GLN88 |
C | LEU48 |
C | ALA87 |
C | GLN88 |
C | EDO709 |
site_id | CC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO C 704 |
Chain | Residue |
B | LEU47 |
B | LEU48 |
B | PHE49 |
C | TYR137 |
C | GLN138 |
site_id | CC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO C 705 |
Chain | Residue |
C | ARG129 |
C | ALA131 |
C | HOH941 |
site_id | CC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CL C 706 |
Chain | Residue |
C | ASN120 |
C | LYS364 |
C | SER421 |
C | TYR431 |
C | SER433 |
C | TYR435 |
site_id | CC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL C 707 |
Chain | Residue |
C | GLN159 |
C | ASN166 |
C | ILE167 |
site_id | CC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA C 708 |
Chain | Residue |
C | LEU369 |
C | ILE372 |
C | GLU374 |
C | ILE377 |
C | THR414 |
C | GLN417 |
site_id | CC9 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO C 709 |
Chain | Residue |
C | GLN88 |
C | EDO703 |
D | LEU48 |
D | PHE49 |
D | ALA87 |
D | GLN88 |
D | HOH745 |
site_id | DC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO C 710 |
Chain | Residue |
C | THR42 |
C | LYS45 |
D | GLU81 |
site_id | DC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO D 501 |
Chain | Residue |
D | GLU116 |
D | MET349 |
D | HOH682 |
D | HOH699 |
site_id | DC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE EDO D 502 |
Chain | Residue |
D | SER99 |
D | ARG102 |
site_id | DC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL D 503 |
Chain | Residue |
D | GLN159 |
D | ASN166 |
D | ILE167 |
D | HOH810 |
site_id | DC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CL D 504 |
Chain | Residue |
D | ASN120 |
D | LYS364 |
D | SER421 |
D | TYR431 |
D | SER433 |
D | TYR435 |
site_id | DC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL D 505 |
Chain | Residue |
B | ARG185 |
D | ASP279 |
D | PRO280 |
D | ALA281 |
D | HOH769 |
site_id | DC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA D 506 |
Chain | Residue |
D | LEU369 |
D | ILE372 |
D | GLU374 |
D | ILE377 |
D | THR414 |
D | GLN417 |
site_id | DC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO D 507 |
Chain | Residue |
C | GLN78 |
C | GLU81 |
D | THR42 |
D | LYS45 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 12 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22683356, ECO:0007744|PDB:4E0U |
Chain | Residue | Details |
A | THR108 | |
D | THR108 | |
D | GLU116 | |
D | PHE223 | |
A | GLU116 | |
A | PHE223 | |
B | THR108 | |
B | GLU116 | |
B | PHE223 | |
C | THR108 | |
C | GLU116 | |
C | PHE223 |
site_id | SWS_FT_FI2 |
Number of Residues | 32 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q4WAW7 |
Chain | Residue | Details |
A | ARG129 | |
B | LYS219 | |
B | TYR221 | |
B | LYS286 | |
B | TYR288 | |
B | TYR366 | |
B | TYR431 | |
B | TYR435 | |
C | ARG129 | |
C | LYS219 | |
C | TYR221 | |
A | LYS219 | |
C | LYS286 | |
C | TYR288 | |
C | TYR366 | |
C | TYR431 | |
C | TYR435 | |
D | ARG129 | |
D | LYS219 | |
D | TYR221 | |
D | LYS286 | |
D | TYR288 | |
A | TYR221 | |
D | TYR366 | |
D | TYR431 | |
D | TYR435 | |
A | LYS286 | |
A | TYR288 | |
A | TYR366 | |
A | TYR431 | |
A | TYR435 | |
B | ARG129 |