4E08

Crystal structure of Drosophila melanogaster DJ-1beta

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0006517	biological_process	protein deglycosylation
A	0006979	biological_process	response to oxidative stress
A	0008344	biological_process	adult locomotory behavior
A	0008345	biological_process	larval locomotory behavior
A	0009438	biological_process	methylglyoxal metabolic process
A	0010310	biological_process	regulation of hydrogen peroxide metabolic process
A	0034614	biological_process	cellular response to reactive oxygen species
A	0036524	molecular_function	protein deglycase activity
A	0036530	biological_process	protein deglycation, methylglyoxal removal
A	0046295	biological_process	glycolate biosynthetic process
A	0048167	biological_process	regulation of synaptic plasticity
A	0048640	biological_process	negative regulation of developmental growth
A	0051896	biological_process	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0051920	molecular_function	peroxiredoxin activity
A	0098869	biological_process	cellular oxidant detoxification
A	1900073	biological_process	regulation of neuromuscular synaptic transmission
A	1903189	biological_process	glyoxal metabolic process
A	1905446	biological_process	regulation of mitochondrial ATP synthesis coupled electron transport
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0006517	biological_process	protein deglycosylation
B	0006979	biological_process	response to oxidative stress
B	0008344	biological_process	adult locomotory behavior
B	0008345	biological_process	larval locomotory behavior
B	0009438	biological_process	methylglyoxal metabolic process
B	0010310	biological_process	regulation of hydrogen peroxide metabolic process
B	0034614	biological_process	cellular response to reactive oxygen species
B	0036524	molecular_function	protein deglycase activity
B	0036530	biological_process	protein deglycation, methylglyoxal removal
B	0046295	biological_process	glycolate biosynthetic process
B	0048167	biological_process	regulation of synaptic plasticity
B	0048640	biological_process	negative regulation of developmental growth
B	0051896	biological_process	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B	0051920	molecular_function	peroxiredoxin activity
B	0098869	biological_process	cellular oxidant detoxification
B	1900073	biological_process	regulation of neuromuscular synaptic transmission
B	1903189	biological_process	glyoxal metabolic process
B	1905446	biological_process	regulation of mitochondrial ATP synthesis coupled electron transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 201

Chain	Residue
A	GLN59
A	GLN130
A	ASN133
A	HOH356
A	HOH373

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"Q99497","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"Cysteine sulfinic acid (-SO2H)","evidences":[{"source":"PubMed","id":"16894167","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Cysteine sulfinic acid (-SO2H); alternate","evidences":[{"source":"PubMed","id":"16894167","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22515803","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---