4DZ2
Crystal structure of a Peptidyl-prolyl cis-trans isomerase with surface mutation R92G from Burkholderia pseudomallei complexed with FK506
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FK5 A 200 |
| Chain | Residue |
| A | TYR33 |
| A | TYR89 |
| A | ILE98 |
| A | PHE106 |
| A | HOH383 |
| A | HOH389 |
| A | HOH403 |
| B | GLY60 |
| B | MET61 |
| B | FK5200 |
| A | PHE43 |
| A | ASP44 |
| A | PHE53 |
| A | MET61 |
| A | VAL62 |
| A | ILE63 |
| A | TRP66 |
| A | GLY88 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 201 |
| Chain | Residue |
| A | ASP51 |
| A | PRO52 |
| A | ASP112 |
| A | VAL113 |
| A | HOH369 |
| A | HOH370 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FK5 B 200 |
| Chain | Residue |
| A | GLY60 |
| A | MET61 |
| A | FK5200 |
| B | TYR33 |
| B | PHE43 |
| B | ASP44 |
| B | ARG49 |
| B | PHE53 |
| B | MET61 |
| B | VAL62 |
| B | ILE63 |
| B | TRP66 |
| B | GLY88 |
| B | TYR89 |
| B | PHE106 |
| B | HOH359 |
| B | HOH391 |
| B | HOH403 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 201 |
| Chain | Residue |
| B | ASP51 |
| B | PRO52 |
| B | ASP112 |
| B | VAL113 |
| B | HOH364 |
| B | HOH365 |
