4DYJ

Crystal structure of a broad specificity amino acid racemase (Bar) within internal aldimine linkage

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0006522	biological_process	alanine metabolic process
A	0008784	molecular_function	alanine racemase activity
A	0016853	molecular_function	isomerase activity
B	0003824	molecular_function	catalytic activity
B	0006522	biological_process	alanine metabolic process
B	0008784	molecular_function	alanine racemase activity
B	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 501

Chain	Residue
A	ALA390
A	LEU391
B	ARG326
B	LYS346

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 502

Chain	Residue
A	ARG326
A	LYS346
B	ALA390
B	LEU391

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 A 503

Chain	Residue
A	ASP409

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 504

Chain	Residue
A	ARG340
A	GLY377
A	GLU378

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 505

Chain	Residue
A	LYS230
A	HIS231
A	LYS233

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 506

Chain	Residue
A	GLN374
A	ALA375

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 507

Chain	Residue
A	MET179
A	ALA180
A	THR181
A	TRP182
A	ARG185

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 508

Chain	Residue
A	TYR301
A	SER348
A	MET349
A	ASN350
A	THR351
A	HOH616
B	LLP75
B	ARG174
B	HOH753

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 501

Chain	Residue
B	VAL408
B	ASP409

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 502

Chain	Residue
B	ARG340
B	GLY377
B	GLU378

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 503

Chain	Residue
B	HIS333
B	PRO342

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 504

Chain	Residue
B	GLN374
B	ALA375

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 505

Chain	Residue
B	THR181
B	TRP182
B	SER183
B	GLN190

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 506

Chain	Residue
B	HIS339
B	ARG340
B	PHE359

---

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 507

Chain	Residue
B	LYS211
B	ARG215

---

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 508

Chain	Residue
A	LLP75
A	ARG174
B	TYR301
B	SER348
B	MET349
B	ASN350
B	HOH635

---

Functional Information from PROSITE/UniProt

site_id	PS00395
Number of Residues	11
Details	ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AVlKADAYGHG

Chain	Residue	Details
A	ALA72-GLY82

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_02212","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23118975","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02212","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"HAMAP-Rule","id":"MF_02212","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23118975","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---