4DWX

Crystal Structure of a Family GH-19 Chitinase from rye seeds

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0004568	molecular_function	chitinase activity
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0006032	biological_process	chitin catabolic process
A	0008061	molecular_function	chitin binding
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0031640	biological_process	killing of cells of another organism
A	0050832	biological_process	defense response to fungus
B	0000272	biological_process	polysaccharide catabolic process
B	0004568	molecular_function	chitinase activity
B	0005576	cellular_component	extracellular region
B	0005975	biological_process	carbohydrate metabolic process
B	0006032	biological_process	chitin catabolic process
B	0008061	molecular_function	chitin binding
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0016998	biological_process	cell wall macromolecule catabolic process
B	0031640	biological_process	killing of cells of another organism
B	0050832	biological_process	defense response to fungus

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE MES A 301

Chain	Residue
A	ILE117
A	HOH625
A	HOH634
A	GLN118
A	LEU119
A	SER120
A	ASN124
A	PHE157
A	ILE198
A	HOH451
A	HOH476

---

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE SO4 A 302

Chain	Residue
A	HIS8
A	ASP12
A	ARG18
A	TYR29
A	THR30
A	TYR31
A	ZN304
A	HOH415
A	HOH423
A	HOH425
A	HOH589
B	ASP51
B	HOH433

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 303

Chain	Residue
A	SER100
A	GLN102
A	TRP103
B	SER100
B	GLN102
B	TRP103

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 304

Chain	Residue
A	HIS8
A	ASP12
A	SO4302
B	ASP51

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 305

Chain	Residue
A	HIS17
A	ASP20
A	HOH590
B	ASP232

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 306

Chain	Residue
A	HIS121
A	HOH428
A	HOH479
A	HOH501
B	HIS206

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 307

Chain	Residue
A	HIS206
A	HOH532
A	HOH554
A	HOH618
B	HIS121

---

site_id	AC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MES B 301

Chain	Residue
B	ILE117
B	GLN118
B	LEU119
B	SER120
B	ASN124
B	ILE198
B	HOH440
B	HOH452
B	HOH490
B	HOH580

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 302

Chain	Residue
B	HIS8
B	ASP12
B	ARG18
B	THR30
B	TYR31
B	ZN303
B	HOH516
B	HOH685

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 303

Chain	Residue
B	HIS8
B	ASP12
B	SO4302
B	HOH467

---

Functional Information from PROSITE/UniProt

site_id	PS00773
Number of Residues	23
Details	CHITINASE_19_1 Chitinases family 19 signature 1. Cqakg.FYTydaFVaAanaFpgFG

Chain	Residue	Details
A	CYS23-GLY45

---

site_id	PS00774
Number of Residues	11
Details	CHITINASE_19_2 Chitinases family 19 signature 2. VSFkTALWFWM

Chain	Residue	Details
A	VAL149-MET159

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P29022

Chain	Residue	Details
A	GLU67
B	GLU67

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: May be involved in substrate-binding => ECO:0000269|Ref.5

Chain	Residue	Details
A	TRP72
B	TRP72

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: May be involved in substrate-binding => ECO:0000269|PubMed:9532801

Chain	Residue	Details
A	ASP95
B	ASP95

---