4DVG
Crystal structure of E. histolytica Formin1 bound to EhRho1-GTPgammaS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0007264 | biological_process | small GTPase-mediated signal transduction |
| B | 0003779 | molecular_function | actin binding |
| B | 0016043 | biological_process | cellular component organization |
| B | 0030036 | biological_process | actin cytoskeleton organization |
| B | 0031267 | molecular_function | small GTPase binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GSP A 200 |
| Chain | Residue |
| A | ALA30 |
| A | LYS133 |
| A | ASP135 |
| A | LEU136 |
| A | GLN154 |
| A | LYS155 |
| A | SER165 |
| A | SER166 |
| A | VAL167 |
| A | MG201 |
| A | VAL31 |
| A | GLY32 |
| A | LYS33 |
| A | THR34 |
| A | CYS35 |
| A | TYR49 |
| A | THR52 |
| A | GLY77 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 201 |
| Chain | Residue |
| A | THR34 |
| A | THR52 |
| A | GSP200 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 11 |
| Details | Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"21930699","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"23050667","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 19 |
| Details | Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"21930699","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"23050667","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21930699","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"23050667","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3REF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3REG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DVG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21930699","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3REG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21930699","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23050667","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3REG","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"4DVG","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"3REF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
