Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | ARG50 |
| A | TYR51 |
| A | GLN53 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | TYR51 |
| A | GLN53 |
| A | GLN55 |
| A | LYS218 |
| A | HOH725 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | GLU134 |
| A | SER139 |
| A | GLN143 |
| A | HOH679 |
| A | ARG96 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 404 |
| Chain | Residue |
| A | SER22 |
| A | PRO23 |
| A | SER58 |
| A | HIS145 |
| A | PRO147 |
| A | HOH554 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR CHAIN B OF 8-MER PEPTIDE INHIBITOR |
| Chain | Residue |
| A | GLY11 |
| A | LEU30 |
| A | ASP32 |
| A | GLY34 |
| A | VAL69 |
| A | PRO70 |
| A | TYR71 |
| A | THR72 |
| A | GLN73 |
| A | PHE108 |
| A | ILE110 |
| A | ILE126 |
| A | LEU188 |
| A | TYR190 |
| A | TRP197 |
| A | TYR198 |
| A | ASP228 |
| A | GLY230 |
| A | THR231 |
| A | THR232 |
| A | ARG235 |
| A | HOH547 |
| A | HOH581 |
| A | HOH593 |
| A | HOH680 |
| B | HOH101 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"17425515","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19011241","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
