4DU7
Crystal structure of Staphylococcus epidermidis mevalonate diphosphate decarboxylase complexed with substrate mevalonate diphosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE DP6 A 401 |
| Chain | Residue |
| A | ALA14 |
| A | SER192 |
| A | ARG193 |
| A | MET196 |
| A | ASP283 |
| A | HOH528 |
| A | HOH601 |
| A | HOH640 |
| A | TYR18 |
| A | LYS21 |
| A | ILE27 |
| A | SER107 |
| A | SER139 |
| A | GLY140 |
| A | SER141 |
| A | ARG144 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE DP6 B 401 |
| Chain | Residue |
| B | ALA14 |
| B | TYR18 |
| B | LYS21 |
| B | SER107 |
| B | SER139 |
| B | GLY140 |
| B | SER141 |
| B | ARG144 |
| B | SER192 |
| B | ARG193 |
| B | MET196 |
| B | ASP283 |
| B | HOH508 |
| B | HOH597 |
| B | HOH619 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 402 |
| Chain | Residue |
| A | VAL98 |
| A | PRO99 |
| B | PRO99 |
| B | THR100 |
| B | HOH556 |
