4DTL

Structure of a VgrG Vibrio cholerae toxin ACD domain in complex with ATP and Mn++

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007015	biological_process	actin filament organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE ATP A 401

Chain	Residue
A	PHE4
A	GLN162
A	THR164
A	ARG268
A	ILE321
A	LEU337
A	MN403
A	MN404
A	SO4405
A	HOH513
A	HOH516
A	SER12
A	HOH549
A	HOH601
A	HOH811
A	GLY14
A	ILE15
A	GLU16
A	GLU78
A	VAL80
A	SER81
A	PRO83

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 402

Chain	Residue
A	GLN32
A	LYS50
A	SER56
A	HIS75
A	HOH725

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 403

Chain	Residue
A	GLU16
A	GLN162
A	GLU339
A	ATP401

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN A 404

Chain	Residue
A	GLU16
A	GLU78
A	ATP401

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 405

Chain	Residue
A	PRO257
A	LYS260
A	ARG341
A	ATP401
A	HOH805

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 406

Chain	Residue
A	ALA141
A	GLY142
A	ASN143
A	GLY144
A	ILE145
A	SER146
A	HOH589
A	HOH887

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 407

Chain	Residue
A	TRP101
A	HIS105
A	ILE121
A	SER123
A	GLU124
A	HOH560

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PDB","id":"4GQK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"A0A0H3AIG7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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