4DTL
Structure of a VgrG Vibrio cholerae toxin ACD domain in complex with ATP and Mn++
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007015 | biological_process | actin filament organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ATP A 401 |
| Chain | Residue |
| A | PHE4 |
| A | GLN162 |
| A | THR164 |
| A | ARG268 |
| A | ILE321 |
| A | LEU337 |
| A | MN403 |
| A | MN404 |
| A | SO4405 |
| A | HOH513 |
| A | HOH516 |
| A | SER12 |
| A | HOH549 |
| A | HOH601 |
| A | HOH811 |
| A | GLY14 |
| A | ILE15 |
| A | GLU16 |
| A | GLU78 |
| A | VAL80 |
| A | SER81 |
| A | PRO83 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | GLN32 |
| A | LYS50 |
| A | SER56 |
| A | HIS75 |
| A | HOH725 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 403 |
| Chain | Residue |
| A | GLU16 |
| A | GLN162 |
| A | GLU339 |
| A | ATP401 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN A 404 |
| Chain | Residue |
| A | GLU16 |
| A | GLU78 |
| A | ATP401 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 405 |
| Chain | Residue |
| A | PRO257 |
| A | LYS260 |
| A | ARG341 |
| A | ATP401 |
| A | HOH805 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 406 |
| Chain | Residue |
| A | ALA141 |
| A | GLY142 |
| A | ASN143 |
| A | GLY144 |
| A | ILE145 |
| A | SER146 |
| A | HOH589 |
| A | HOH887 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 407 |
| Chain | Residue |
| A | TRP101 |
| A | HIS105 |
| A | ILE121 |
| A | SER123 |
| A | GLU124 |
| A | HOH560 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22898822, ECO:0007744|PDB:4DTH, ECO:0007744|PDB:4DTL, ECO:0007744|PDB:4E1C, ECO:0007744|PDB:4E1D, ECO:0007744|PDB:4E1F |
| Chain | Residue | Details |
| A | SER12 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22898822, ECO:0007744|PDB:4DTH, ECO:0007744|PDB:4DTL, ECO:0007744|PDB:4E1D |
| Chain | Residue | Details |
| A | GLU16 | |
| A | GLU78 | |
| A | GLN162 | |
| A | GLU339 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22898822, ECO:0007744|PDB:4DTF, ECO:0007744|PDB:4DTH, ECO:0007744|PDB:4DTL, ECO:0007744|PDB:4E1C, ECO:0007744|PDB:4E1D, ECO:0007744|PDB:4E1F |
| Chain | Residue | Details |
| A | SER81 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22898822, ECO:0007744|PDB:4DTH, ECO:0007744|PDB:4E1D |
| Chain | Residue | Details |
| A | ARG268 |
