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4DSS

Crystal structure of peroxiredoxin Ahp1 from Saccharomyces cerevisiae in complex with thioredoxin Trx2

Functional Information from GO Data
ChainGOidnamespacecontents
A0004601molecular_functionperoxidase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005777cellular_componentperoxisome
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0008379molecular_functionthioredoxin peroxidase activity
A0010038biological_processresponse to metal ion
A0016491molecular_functionoxidoreductase activity
A0034599biological_processcellular response to oxidative stress
A0042744biological_processhydrogen peroxide catabolic process
A0045454biological_processcell redox homeostasis
A0050821biological_processprotein stabilization
A0098869biological_processcellular oxidant detoxification
A0140824molecular_functionthioredoxin-dependent peroxiredoxin activity
B0000011biological_processvacuole inheritance
B0000103biological_processsulfate assimilation
B0000139cellular_componentGolgi membrane
B0000324cellular_componentfungal-type vacuole
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0006749biological_processglutathione metabolic process
B0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
B0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
B0009263biological_processdeoxyribonucleotide biosynthetic process
B0015031biological_processprotein transport
B0015035molecular_functionprotein-disulfide reductase activity
B0015036molecular_functiondisulfide oxidoreductase activity
B0016020cellular_componentmembrane
B0042144biological_processvacuole fusion, non-autophagic
B0045454biological_processcell redox homeostasis
B0120124cellular_componentmembrane fusion priming complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Nucleophile
ChainResidueDetails
BCYS31
BSER34

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Deprotonates C-terminal active site Cys
ChainResidueDetails
BASP25

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Contributes to redox potential value
ChainResidueDetails
BGLY32
BPRO33

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
BSER62

site_idSWS_FT_FI5
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
BLYS67
BLYS97

site_idSWS_FT_FI6
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
ALYS48
ALYS113

227344

PDB entries from 2024-11-13

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