4DRP
Evaluation of Synthetic FK506 Analogs as Ligands for the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-((1R,2S)-2-ethyl-1-hydroxy-cyclohexyl)-2-oxoacetyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid from cocrystallization
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 0MD A 201 |
| Chain | Residue |
| A | THR19 |
| A | ILE87 |
| A | TRP90 |
| A | LYS108 |
| A | ALA112 |
| A | TYR113 |
| A | ILE122 |
| A | HOH309 |
| A | HOH315 |
| A | HOH324 |
| A | HOH467 |
| A | GLU20 |
| A | ARG31 |
| A | TYR57 |
| A | PHE67 |
| A | ASP68 |
| A | GLY84 |
| A | GLN85 |
| A | VAL86 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:28147277 |
| Chain | Residue | Details |
| A | LYS28 |
