4DRO
EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR FKBP51 AND FKBP52: COMPLEX OF FKBP51 WITH (1R)-3-(3,4-dimethoxyphenyl)-1-phenylpropyl (2S)-1-{[(1R,2S)-2-ethyl-1-hydroxycyclohexyl](oxo)acetyl}piperidine-2-carboxylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 0MD A 201 |
| Chain | Residue |
| A | TYR57 |
| A | ALA112 |
| A | TYR113 |
| A | HOH379 |
| A | HOH475 |
| A | HOH502 |
| A | PHE67 |
| A | ASP68 |
| A | PHE77 |
| A | GLY84 |
| A | GLN85 |
| A | VAL86 |
| A | ILE87 |
| A | TRP90 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:28147277 |
| Chain | Residue | Details |
| A | LYS28 |
