Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006177 | biological_process | GMP biosynthetic process |
| A | 0006183 | biological_process | GTP biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006177 | biological_process | GMP biosynthetic process |
| B | 0006183 | biological_process | GTP biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ATP A 501 |
| Chain | Residue |
| A | THR134 |
| A | LYS181 |
| A | MN502 |
| A | ATP503 |
| A | MN504 |
| B | ARG136 |
| B | ARG178 |
| B | GLU180 |
| B | ATP501 |
| B | MN502 |
| B | HOH654 |
| A | GLY135 |
| B | HOH700 |
| A | ARG136 |
| A | ASP137 |
| A | THR153 |
| A | LEU158 |
| A | VAL159 |
| A | ILE179 |
| A | GLU180 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 502 |
| Chain | Residue |
| A | GLU180 |
| A | ATP501 |
| A | ATP503 |
| A | MN504 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ATP A 503 |
| Chain | Residue |
| A | VAL94 |
| A | PRO97 |
| A | VAL98 |
| A | PHE118 |
| A | GLY120 |
| A | GLU180 |
| A | LYS181 |
| A | LEU194 |
| A | THR196 |
| A | ARG198 |
| A | ASP199 |
| A | ATP501 |
| A | MN502 |
| A | MN504 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 504 |
| Chain | Residue |
| A | GLU180 |
| A | ATP501 |
| A | MN502 |
| A | ATP503 |
| B | ATP501 |
| B | HOH700 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 505 |
| Chain | Residue |
| A | GLY338 |
| A | GLY339 |
| A | GLY360 |
| A | SER361 |
| A | HOH615 |
| A | HOH697 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 506 |
| Chain | Residue |
| A | HIS89 |
| A | ALA203 |
| A | TYR206 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ATP B 501 |
| Chain | Residue |
| A | ARG136 |
| A | ARG178 |
| A | GLU180 |
| A | ATP501 |
| A | MN504 |
| B | ILE132 |
| B | THR134 |
| B | ARG136 |
| B | ASP137 |
| B | THR153 |
| B | LYS157 |
| B | LEU158 |
| B | VAL159 |
| B | ILE179 |
| B | GLU180 |
| B | LYS181 |
| B | MN502 |
| B | ATP503 |
| B | MN504 |
| B | HOH700 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 502 |
| Chain | Residue |
| A | ATP501 |
| B | GLU180 |
| B | ATP501 |
| B | ATP503 |
| B | MN504 |
| B | HOH654 |
| B | HOH700 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP B 503 |
| Chain | Residue |
| B | VAL94 |
| B | PRO97 |
| B | VAL98 |
| B | PHE118 |
| B | SER119 |
| B | GLY120 |
| B | GLU180 |
| B | LYS181 |
| B | LEU194 |
| B | THR196 |
| B | ARG198 |
| B | ASP199 |
| B | ATP501 |
| B | MN502 |
| B | MN504 |
| B | HOH654 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 504 |
| Chain | Residue |
| B | ATP503 |
| B | GLU180 |
| B | ATP501 |
| B | MN502 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT |
| Chain | Residue | Details |
| A | VAL294-THR306 | |
