4DQR
Ternary complex of Bacillus DNA Polymerase I Large Fragment E658A, DNA duplex, and rCTP (paired with dG of template) in presence of Mn2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| D | 0006260 | biological_process | DNA replication |
| D | 0006261 | biological_process | DNA-templated DNA replication |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE CTP A 901 |
| Chain | Residue |
| A | ARG615 |
| A | MN902 |
| A | HOH1003 |
| A | HOH1032 |
| A | HOH1103 |
| A | HOH1108 |
| A | HOH1202 |
| B | DOC29 |
| C | DG3 |
| C | DG4 |
| A | TYR654 |
| A | GLN656 |
| A | ALA658 |
| A | HIS682 |
| A | ARG702 |
| A | LYS706 |
| A | PHE710 |
| A | ASP830 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 902 |
| Chain | Residue |
| A | ASP653 |
| A | TYR654 |
| A | ASP830 |
| A | CTP901 |
| A | HOH1103 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 903 |
| Chain | Residue |
| A | ARG779 |
| A | ASN780 |
| D | ARG423 |
| D | PRO424 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD A 904 |
| Chain | Residue |
| A | HOH1007 |
| A | HOH1028 |
| A | HOH1195 |
| D | LEU352 |
| D | LYS383 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE CTP D 901 |
| Chain | Residue |
| D | ARG615 |
| D | GLN656 |
| D | ALA658 |
| D | HIS682 |
| D | ARG702 |
| D | LYS706 |
| D | PHE710 |
| D | ASP830 |
| D | MN902 |
| D | HOH1001 |
| D | HOH1015 |
| D | HOH1018 |
| D | HOH1020 |
| D | HOH1041 |
| D | HOH1131 |
| D | HOH1158 |
| D | HOH1202 |
| D | HOH1314 |
| D | HOH1418 |
| E | DOC29 |
| F | DG3 |
| F | DG4 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN D 902 |
| Chain | Residue |
| D | ASP830 |
| D | CTP901 |
| D | HOH1090 |
| D | HOH1418 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 903 |
| Chain | Residue |
| D | MET299 |
| D | ALA300 |
| D | ARG343 |
| D | ARG677 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD D 904 |
| Chain | Residue |
| A | LEU352 |
| A | LYS383 |
| D | HOH1059 |
| D | HOH1067 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD D 905 |
| Chain | Residue |
| A | GLU501 |
| A | GLY504 |
| A | LYS505 |
| D | ALA353 |
| D | ASP354 |
| D | HOH1193 |
Functional Information from PROSITE/UniProt
| site_id | PS00447 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_A DNA polymerase family A signature. RrqAKavnFGivYgiSdygL |
| Chain | Residue | Details |
| A | ARG702-LEU721 |
