Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
A | 0009085 | biological_process | lysine biosynthetic process |
A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
A | 0009507 | cellular_component | chloroplast |
A | 0016829 | molecular_function | lyase activity |
A | 0019877 | biological_process | diaminopimelate biosynthetic process |
B | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
B | 0009085 | biological_process | lysine biosynthetic process |
B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
B | 0009507 | cellular_component | chloroplast |
B | 0016829 | molecular_function | lyase activity |
B | 0019877 | biological_process | diaminopimelate biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE NA A 401 |
Chain | Residue |
A | PHE345 |
A | VAL346 |
A | GLY347 |
A | NA402 |
A | HOH542 |
A | HOH545 |
A | HOH553 |
A | HOH588 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA A 402 |
Chain | Residue |
A | NA401 |
A | HOH542 |
A | HOH553 |
A | HOH588 |
A | HOH647 |
A | GLU343 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA A 403 |
Chain | Residue |
A | ARG252 |
A | HOH525 |
A | HOH532 |
A | HOH543 |
A | HOH565 |
site_id | AC4 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE LYS A 404 |
Chain | Residue |
A | GLY111 |
A | GLN112 |
A | MET114 |
A | TRP116 |
A | HIS119 |
A | TYR169 |
A | HOH509 |
A | HOH548 |
B | ASN143 |
B | GLU147 |
B | LYS403 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE NA B 401 |
Chain | Residue |
B | PHE345 |
B | VAL346 |
B | GLY347 |
B | NA402 |
B | HOH520 |
B | HOH556 |
B | HOH557 |
B | HOH617 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA B 402 |
Chain | Residue |
B | GLU343 |
B | NA401 |
B | HOH520 |
B | HOH556 |
B | HOH617 |
B | HOH629 |
site_id | AC7 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE LYS B 403 |
Chain | Residue |
A | ASN143 |
A | GLU147 |
A | LYS404 |
B | GLY111 |
B | GLN112 |
B | MET114 |
B | TRP116 |
B | HIS119 |
B | TYR169 |
B | HOH515 |
B | HOH528 |
B | HOH588 |
Functional Information from PROSITE/UniProt
site_id | PS00665 |
Number of Residues | 18 |
Details | DHDPS_1 Dihydrodipicolinate synthase signature 1. GVIvgGTTGEGqlmswdE |
Chain | Residue | Details |
A | GLY101-GLU118 | |
site_id | PS00666 |
Number of Residues | 31 |
Details | DHDPS_2 Dihydrodipicolinate synthase signature 2. YNVPgrTgqdIppraifklsqnpn.LaGVKEC |
Chain | Residue | Details |
A | TYR194-CYS224 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor/acceptor => ECO:0000250 |
Chain | Residue | Details |
A | TYR194 | |
B | TYR194 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Schiff-base intermediate with substrate => ECO:0000250 |
Chain | Residue | Details |
A | LYS222 | |
B | LYS222 | |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | THR108 | |
A | ILE261 | |
B | THR108 | |
B | ILE261 | |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | SITE: Part of a proton relay during catalysis => ECO:0000250 |
Chain | Residue | Details |
A | THR107 | |
A | TYR170 | |
B | THR107 | |
B | TYR170 | |