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4DLV

H-Ras Set 2 CaCl2/DTT, ordered off

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
A0007165biological_processsignal transduction
A0016020cellular_componentmembrane
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA A 201
ChainResidue
APHE28
AASP30
AGLU31
AASP33
AHOH307
AHOH431

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 202
ChainResidue
AHOH301
AHOH428
ASER17
ATHR35
AGNP204

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 203
ChainResidue
AHOH337
AHOH337
AHOH337
AHOH358
AHOH358
AHOH358

site_idAC4
Number of Residues29
DetailsBINDING SITE FOR RESIDUE GNP A 204
ChainResidue
AGLY12
AGLY13
AVAL14
AGLY15
ALYS16
ASER17
AALA18
APHE28
AVAL29
AASP30
AGLU31
ATYR32
APRO34
ATHR35
AGLY60
AASN116
ALYS117
AASP119
ALEU120
ASER145
AALA146
ALYS147
AMG202
AHOH301
AHOH303
AHOH324
AHOH331
AHOH425
AHOH428

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE DTT A 205
ChainResidue
AARG68
AASP92
AGLN95

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 206
ChainResidue
AARG102
AARG102
AASP105
AASP105
AHOH380
AHOH380

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsBINDING: BINDING => ECO:0000269|PubMed:16698776
ChainResidueDetails
AGLY13
AVAL29
AALA59
AASN116
ASER145

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N-acetylmethionine; in GTPase HRas; alternate => ECO:0000269|Ref.12
ChainResidueDetails
AMET1

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: N-acetylthreonine; in GTPase HRas, N-terminally processed => ECO:0000269|Ref.12
ChainResidueDetails
ATHR2

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: S-nitrosocysteine => ECO:0000269|PubMed:9020151
ChainResidueDetails
ACYS118

site_idSWS_FT_FI5
Number of Residues1
DetailsCARBOHYD: (Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL => ECO:0000269|PubMed:19744486, ECO:0000269|PubMed:8626575, ECO:0000269|PubMed:8626586, ECO:0000269|PubMed:9632667
ChainResidueDetails
ATHR35

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PDB entries from 2024-12-18

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