4DLK
Crystal Structure of ATP-Ca++ complex of purK: N5-carboxyaminoimidazole ribonucleotide synthetase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0034028 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide synthase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016874 | molecular_function | ligase activity |
| B | 0034028 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide synthase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 401 |
| Chain | Residue |
| A | GLU268 |
| A | ATP404 |
| A | HOH526 |
| A | HOH529 |
| A | HOH549 |
| A | HOH561 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | ATP405 |
| A | HOH534 |
| A | HOH537 |
| A | HOH561 |
| A | GLU255 |
| A | GLU268 |
| A | ATP404 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | ASP154 |
| A | ATP404 |
| A | ATP405 |
| A | HOH533 |
| A | HOH543 |
| A | HOH551 |
| site_id | AC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE ATP A 404 |
| Chain | Residue |
| A | ARG107 |
| A | LYS147 |
| A | ASP154 |
| A | GLY155 |
| A | GLN158 |
| A | GLU182 |
| A | LYS183 |
| A | TRP184 |
| A | VAL185 |
| A | PHE187 |
| A | GLU190 |
| A | PHE257 |
| A | ASN267 |
| A | GLU268 |
| A | CA401 |
| A | CA402 |
| A | CA403 |
| A | ATP405 |
| A | HOH526 |
| A | HOH529 |
| A | HOH534 |
| A | HOH537 |
| A | HOH539 |
| A | HOH543 |
| A | HOH558 |
| A | HOH570 |
| A | HOH622 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ATP A 405 |
| Chain | Residue |
| A | GLU76 |
| A | TYR153 |
| A | HIS213 |
| A | GLU255 |
| A | ARG272 |
| A | HIS274 |
| A | ASN275 |
| A | LYS348 |
| A | CA402 |
| A | CA403 |
| A | ATP404 |
| A | ATP406 |
| A | HOH505 |
| A | HOH517 |
| A | HOH533 |
| A | HOH535 |
| A | HOH543 |
| A | HOH545 |
| A | HOH561 |
| A | HOH584 |
| A | HOH619 |
| A | HOH627 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ATP A 406 |
| Chain | Residue |
| A | PHE77 |
| A | LYS340 |
| A | ARG347 |
| A | ATP405 |
| A | HOH542 |
| A | HOH556 |
| A | HOH604 |
| A | HOH619 |
| A | HOH646 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 407 |
| Chain | Residue |
| A | ALA46 |
| A | GLN47 |
| A | VAL48 |
| A | ALA49 |
| B | GLN47 |
| B | VAL48 |
| B | ALA49 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 401 |
| Chain | Residue |
| B | GLU255 |
| B | GLU268 |
| B | ATP403 |
| B | HOH550 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 402 |
| Chain | Residue |
| B | GLY152 |
| B | GLU268 |
| B | ATP403 |
| site_id | BC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE ATP B 403 |
| Chain | Residue |
| B | GLU182 |
| B | LYS183 |
| B | TRP184 |
| B | VAL185 |
| B | PHE187 |
| B | GLU190 |
| B | HIS213 |
| B | ASN216 |
| B | GLU255 |
| B | PHE257 |
| B | ASN267 |
| B | GLU268 |
| B | CA401 |
| B | CA402 |
| B | HOH510 |
| B | HOH561 |
| B | HOH583 |
| B | HOH606 |
| B | HOH623 |
| B | ARG107 |
| B | VAL145 |
| B | LYS147 |
| B | GLY152 |
| B | TYR153 |
| B | ASP154 |
| B | GLY155 |
| B | GLN158 |
