4DKB

Crystal Structure of Trypanosoma brucei dUTPase with dUpNp and Ca2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004170	molecular_function	dUTP diphosphatase activity
A	0005654	cellular_component	nucleoplasm
A	0005829	cellular_component	cytosol
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 301

Chain	Residue
A	GLU48
A	GLU51
A	CA302
A	DUN303
A	HOH401
A	HOH402

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 302

Chain	Residue
A	ASP79
A	CA301
A	DUN303
A	HOH403
A	GLU48
A	GLU51
A	GLU76

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site_id	AC3
Number of Residues	22
Details	BINDING SITE FOR RESIDUE DUN A 303

Chain	Residue
A	GLN21
A	LEU24
A	ASN25
A	TRP41
A	GLU48
A	GLU51
A	LYS59
A	TRP60
A	TRP61
A	ASP79
A	HIS82
A	PHE83
A	LYS208
A	ASN212
A	ARG215
A	TYR220
A	LYS227
A	ASN235
A	CA301
A	CA302
A	HOH403
A	HOH404

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