4DIE

Crystal structure of a cytidylate kinase CmK from Mycobacterium abscessus bound to cytidine-5'-monophosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004127	molecular_function	cytidylate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006220	biological_process	pyrimidine nucleotide metabolic process
A	0015949	biological_process	nucleobase-containing small molecule interconversion
A	0016301	molecular_function	kinase activity
A	0036430	molecular_function	CMP kinase activity
A	0036431	molecular_function	dCMP kinase activity
A	0044271	biological_process	obsolete cellular nitrogen compound biosynthetic process
A	0044281	biological_process	small molecule metabolic process
A	0046940	biological_process	nucleoside monophosphate phosphorylation
B	0004127	molecular_function	cytidylate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006220	biological_process	pyrimidine nucleotide metabolic process
B	0015949	biological_process	nucleobase-containing small molecule interconversion
B	0016301	molecular_function	kinase activity
B	0036430	molecular_function	CMP kinase activity
B	0036431	molecular_function	dCMP kinase activity
B	0044271	biological_process	obsolete cellular nitrogen compound biosynthetic process
B	0044281	biological_process	small molecule metabolic process
B	0046940	biological_process	nucleoside monophosphate phosphorylation
C	0004127	molecular_function	cytidylate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0006220	biological_process	pyrimidine nucleotide metabolic process
C	0015949	biological_process	nucleobase-containing small molecule interconversion
C	0016301	molecular_function	kinase activity
C	0036430	molecular_function	CMP kinase activity
C	0036431	molecular_function	dCMP kinase activity
C	0044271	biological_process	obsolete cellular nitrogen compound biosynthetic process
C	0044281	biological_process	small molecule metabolic process
C	0046940	biological_process	nucleoside monophosphate phosphorylation
D	0004127	molecular_function	cytidylate kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006139	biological_process	nucleobase-containing compound metabolic process
D	0006220	biological_process	pyrimidine nucleotide metabolic process
D	0015949	biological_process	nucleobase-containing small molecule interconversion
D	0016301	molecular_function	kinase activity
D	0036430	molecular_function	CMP kinase activity
D	0036431	molecular_function	dCMP kinase activity
D	0044271	biological_process	obsolete cellular nitrogen compound biosynthetic process
D	0044281	biological_process	small molecule metabolic process
D	0046940	biological_process	nucleoside monophosphate phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE C5P A 301

Chain	Residue
A	THR30
A	ARG126
A	ASP127
A	GLY31
A	TYR34
A	ARG35
A	ARG86
A	VAL94
A	SER95
A	SER98
A	ARG104

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 A 302

Chain	Residue
A	GLY9
A	THR10
A	GLY11
A	LYS12
A	SER13
A	HOH412

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE C5P B 301

Chain	Residue
B	THR30
B	GLY31
B	TYR34
B	ARG35
B	VAL94
B	SER95
B	SER98
B	ARG104
B	GLY125
B	ARG126
B	ASP127
B	HOH425

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 B 302

Chain	Residue
B	SER8
B	GLY9
B	THR10
B	GLY11
B	LYS12

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE C5P C 301

Chain	Residue
C	THR30
C	GLY31
C	TYR34
C	ARG35
C	VAL94
C	SER95
C	SER98
C	ARG104
C	ARG126
C	ASP127

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 C 302

Chain	Residue
C	GLY9
C	GLY11
C	LYS12
C	SER13

---

site_id	AC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE C5P D 301

Chain	Residue
D	THR30
D	GLY31
D	TYR34
D	ARG35
D	VAL94
D	SER95
D	SER98
D	ARG104
D	ARG126
D	ASP127
D	HOH410
D	HOH435

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 D 302

Chain	Residue
D	SER8
D	GLY9
D	THR10
D	GLY11
D	LYS12
D	SER13
D	HOH417

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