4DGY

Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody HCV1, C2 form

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL H 301

Chain	Residue
H	SER172
H	LEU189
H	GLY190
H	LYS210
H	HOH473

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL H 302

Chain	Residue
H	GLU1
H	VAL2
H	PHE102

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL H 303

Chain	Residue
H	PRO149
H	VAL150
H	TYR145

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL H 304

Chain	Residue
H	TYR59
H	ARG64

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site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL L 301

Chain	Residue
H	PHE166
H	PRO167
H	VAL169
H	SER177
H	LEU178
H	SER179
L	SER162
L	SER176
L	ASN177
L	THR178
L	HOH429

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site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL L 302

Chain	Residue
H	ASN31
H	ARG100
H	ASP101
H	HOH523
L	TYR49
L	ALA55
L	THR56
L	HOH542

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (high mannose) asparagine; by host","evidences":[{"source":"UniProtKB","id":"P27958","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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