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4DG8

Structure of PA1221, an NRPS protein containing adenylation and PCP domains

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0005737cellular_componentcytoplasm
A0031177molecular_functionphosphopantetheine binding
A0043041biological_processamino acid activation for nonribosomal peptide biosynthetic process
A0044550biological_processsecondary metabolite biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues22
DetailsBINDING SITE FOR RESIDUE AMP A 701
ChainResidue
AGLY282
ATHR310
AASP400
APHE412
ALYS421
AARG426
ABU3702
AHOH833
AHOH861
AHOH920
AHOH973
AGLY283
AHOH991
AHOH1008
AHOH1043
AASP284
AILE285
AASN305
AGLY306
ATYR307
AGLY308
APRO309

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE BU3 A 702
ChainResidue
AGLY283
ALYS421
AAMP701
AHOH919
AHOH1024

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE BU3 A 703
ChainResidue
ASER209
ATRP256
ATHR258
AHOH844
AHOH986

Functional Information from PROSITE/UniProt
site_idPS00455
Number of Residues12
DetailsAMP_BINDING Putative AMP-binding domain signature. INFSSGTTGrPK
ChainResidueDetails
AILE167-LYS178

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PDB entries from 2024-07-24

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