4DFW
Oxime-based Post Solid-phase Peptide Diversification: Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 701 |
| Chain | Residue |
| A | LYS388 |
| A | PRO389 |
| A | SER390 |
| A | HOH824 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 702 |
| Chain | Residue |
| A | ARG560 |
| A | THR561 |
| A | HOH876 |
| A | HOH1014 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR CHAIN D OF PEPTIDE |
| Chain | Residue |
| A | TRP414 |
| A | VAL415 |
| A | ASP416 |
| A | TYR421 |
| A | THR459 |
| A | TYR481 |
| A | TYR485 |
| A | LEU490 |
| A | LEU491 |
| A | ARG516 |
| A | HIS538 |
| A | LYS540 |
| A | HOH802 |
| A | HOH836 |
| A | HOH843 |
| A | HOH956 |
| A | HOH1040 |
| D | HOH101 |
| D | HOH102 |
| D | HOH103 |
| D | HOH104 |
| D | HOH105 |
| D | HOH107 |
| D | HOH109 |
| A | LYS413 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | SER375 | |
| A | SER450 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | THR498 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23455478 |
| Chain | Residue | Details |
| A | LYS492 |
