4DDJ

Crystal structure of saposin A in complex with lauryldimethylamine-N-oxide (LDAO)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005764	cellular_component	lysosome
A	0006629	biological_process	lipid metabolic process
A	0006665	biological_process	sphingolipid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE LDA A 101

Chain	Residue
A	TYR30
A	THR34
A	TRP37

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LDA A 102

Chain	Residue
A	ASP20
A	THR23
A	GLU26
A	LDA103
A	LDA109

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LDA A 103

Chain	Residue
A	TYR30
A	LDA102
A	LDA109
A	GLU26

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LDA A 104

Chain	Residue
A	LEU76
A	ASN77
A	LDA106
A	LDA114
A	LDA117

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LDA A 105

Chain	Residue
A	TYR54
A	ALA75
A	ASN77
A	LDA110
A	LDA117
A	LDA118

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LDA A 106

Chain	Residue
A	VAL10
A	LDA104
A	LDA115
A	HOH232

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LDA A 107

Chain	Residue
A	TYR30
A	LDA108
A	LDA109
A	HOH252

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE LDA A 108

Chain	Residue
A	LDA107
A	LDA114
A	LDA119

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LDA A 109

Chain	Residue
A	LDA102
A	LDA103
A	LDA107
A	LDA119

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE LDA A 110

Chain	Residue
A	ALA75
A	LDA105

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LDA A 111

Chain	Residue
A	GLU65
A	GLU71
A	LDA112
A	LDA113
A	LDA116
A	HOH253

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE LDA A 112

Chain	Residue
A	LDA111
A	LDA116
A	LDA119

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LDA A 113

Chain	Residue
A	VAL10
A	MET66
A	LDA111
A	LDA115
A	LDA119

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LDA A 114

Chain	Residue
A	TRP37
A	LDA104
A	LDA108
A	LDA117

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE LDA A 115

Chain	Residue
A	LEU38
A	MET43
A	LDA106
A	LDA113
A	LDA117
A	LDA120
A	LDA120

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE LDA A 116

Chain	Residue
A	LDA111
A	LDA112

---

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE LDA A 117

Chain	Residue
A	THR34
A	TRP37
A	CYS47
A	VAL51
A	LDA104
A	LDA105
A	LDA114
A	LDA115

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LDA A 118

Chain	Residue
A	GLU25
A	LEU28
A	GLU32
A	TYR54
A	ILE61
A	LDA105

---

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LDA A 119

Chain	Residue
A	MET17
A	LEU18
A	LDA108
A	LDA109
A	LDA112
A	LDA113

---

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE LDA A 120

Chain	Residue
A	ASP9
A	LDA115
A	LDA115

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00415","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19167329","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2842863","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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