4DD5

Biosynthetic Thiolase (ThlA1) from Clostridium difficile

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
A	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from PROSITE/UniProt

site_id	PS00098
Number of Residues	19
Details	THIOLASE_1 Thiolases acyl-enzyme intermediate signature. INIvCGSGLrSVsmasqlI

Chain	Residue	Details
A	ILE89-ILE107

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site_id	PS00737
Number of Residues	17
Details	THIOLASE_2 Thiolases signature 2. NvnGGaIAiGHPiGcSG

Chain	Residue	Details
A	ASN343-GLY359

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Acyl-thioester intermediate => ECO:0000250|UniProtKB:P45359

Chain	Residue	Details
A	CYS93

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P45359

Chain	Residue	Details
A	HIS353
A	CYS383

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