4DCN

Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005802	cellular_component	trans-Golgi network
A	0005829	cellular_component	cytosol
A	0006886	biological_process	intracellular protein transport
A	0007030	biological_process	Golgi organization
A	0008047	molecular_function	enzyme activator activity
A	0009404	biological_process	toxin metabolic process
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
A	0019904	molecular_function	protein domain specific binding
A	0032588	cellular_component	trans-Golgi network membrane
A	0034067	biological_process	protein localization to Golgi apparatus
A	0042147	biological_process	retrograde transport, endosome to Golgi
A	0046872	molecular_function	metal ion binding
A	1990583	molecular_function	phospholipase D activator activity
B	0000139	cellular_component	Golgi membrane
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005794	cellular_component	Golgi apparatus
B	0005802	cellular_component	trans-Golgi network
B	0005829	cellular_component	cytosol
B	0006886	biological_process	intracellular protein transport
B	0007030	biological_process	Golgi organization
B	0008047	molecular_function	enzyme activator activity
B	0009404	biological_process	toxin metabolic process
B	0016020	cellular_component	membrane
B	0016192	biological_process	vesicle-mediated transport
B	0019904	molecular_function	protein domain specific binding
B	0032588	cellular_component	trans-Golgi network membrane
B	0034067	biological_process	protein localization to Golgi apparatus
B	0042147	biological_process	retrograde transport, endosome to Golgi
B	0046872	molecular_function	metal ion binding
B	1990583	molecular_function	phospholipase D activator activity
C	0019904	molecular_function	protein domain specific binding
D	0019904	molecular_function	protein domain specific binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 201

Chain	Residue
A	THR31
A	ILE46
A	THR48
A	GNP202
A	HOH301
A	HOH302

---

site_id	AC2
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GNP A 202

Chain	Residue
A	GLY29
A	LYS30
A	THR31
A	THR32
A	THR45
A	THR48
A	GLY69
A	GLY70
A	ASN126
A	LYS127
A	ASP129
A	SER159
A	ALA160
A	THR161
A	MG201
A	HOH301
A	HOH302
A	ASP26
A	GLY27
A	ALA28

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 201

Chain	Residue
B	THR31
B	THR48
B	GNP202
B	HOH301
B	HOH302

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GNP B 202

Chain	Residue
B	ASP26
B	GLY27
B	ALA28
B	GLY29
B	LYS30
B	THR31
B	THR32
B	THR45
B	THR48
B	GLY70
B	ASN126
B	LYS127
B	ASP129
B	SER159
B	ALA160
B	THR161
B	MG201
B	HOH301
B	HOH302

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:14580338, ECO:0000269|PubMed:27373159, ECO:0000269|PubMed:27436755

Chain	Residue	Details
A	GLY24
B	ALA160
A	THR45
A	GLY70
A	ASN126
A	ALA160
B	GLY24
B	THR45
B	GLY70
B	ASN126

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:14580338

Chain	Residue	Details
A	THR31
A	THR48
B	THR31
B	THR48

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP67
B	ASP67

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