4DCD
1.6A resolution structure of PolioVirus 3C Protease Containing a covalently bound dipeptidyl inhibitor
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DTT A 201 |
| Chain | Residue |
| A | HIS-1 |
| A | HIS-2 |
| A | HIS-2 |
| A | HIS0 |
| A | LYS12 |
| A | LYS12 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE K36 A 202 |
| Chain | Residue |
| A | GLY128 |
| A | THR142 |
| A | ARG143 |
| A | ALA144 |
| A | CYS147 |
| A | HIS161 |
| A | VAL162 |
| A | GLY163 |
| A | GLY164 |
| A | HOH324 |
| A | HOH340 |
| A | HOH365 |
| A | HIS40 |
| A | ASN126 |
| A | LEU127 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | HIS-3 |
| A | HIS-2 |
| A | GLY1 |
| A | PRO2 |
| A | ARG13 |
| A | HOH377 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 204 |
| Chain | Residue |
| A | ARG79 |
| A | ASN80 |
| A | GLU81 |
| A | HOH376 |
| A | HOH417 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 178 |
| Details | Domain: {"description":"Peptidase C3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01222","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For protease 3C activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01222","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For protease 3C activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01222","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8097606","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
