Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4DC4

Lysozyme Trimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0003824	molecular_function	catalytic activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0008152	biological_process	metabolic process
A	0016231	molecular_function	beta-N-acetylglucosaminidase activity
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium
A	0042802	molecular_function	identical protein binding
A	0050829	biological_process	defense response to Gram-negative bacterium
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
B	0003796	molecular_function	lysozyme activity
B	0003824	molecular_function	catalytic activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0008152	biological_process	metabolic process
B	0016231	molecular_function	beta-N-acetylglucosaminidase activity
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0016998	biological_process	cell wall macromolecule catabolic process
B	0031640	biological_process	killing of cells of another organism
B	0042742	biological_process	defense response to bacterium
B	0042802	molecular_function	identical protein binding
B	0050829	biological_process	defense response to Gram-negative bacterium
B	0050830	biological_process	defense response to Gram-positive bacterium
B	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
C	0003796	molecular_function	lysozyme activity
C	0003824	molecular_function	catalytic activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0008152	biological_process	metabolic process
C	0016231	molecular_function	beta-N-acetylglucosaminidase activity
C	0016787	molecular_function	hydrolase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0016998	biological_process	cell wall macromolecule catabolic process
C	0031640	biological_process	killing of cells of another organism
C	0042742	biological_process	defense response to bacterium
C	0042802	molecular_function	identical protein binding
C	0050829	biological_process	defense response to Gram-negative bacterium
C	0050830	biological_process	defense response to Gram-positive bacterium
C	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 201

Chain	Residue
A	SER24
A	GLY26
A	GLN121

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 203

Chain	Residue
A	ASN65
A	ASP66
A	GLY67
A	THR69
A	SER72

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 204

Chain	Residue
A	ILE58
A	ASN59
A	TRP63
A	ALA107
A	TRP108
A	GLN57

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 205

Chain	Residue
A	VAL2
B	CYS76

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 201

Chain	Residue
B	GLY71
C	ASN103
C	ALA107

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA B 202

Chain	Residue
B	SER60
B	CYS64
B	ASN65
B	ASP66
B	SER72

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 203

Chain	Residue
B	GLU35
B	ASP52
B	GLN57
B	ILE58
B	ASN59
B	TRP108
B	VAL109

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
A	CYS76-CYS94

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE:

Chain	Residue	Details
A	GLU35
A	ASP52
B	GLU35
B	ASP52
C	GLU35
C	ASP52

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING:

Chain	Residue	Details
A	ASP101
B	ASP101
C	ASP101

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
A	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	ASN46
A	ASP48
A	SER50
A	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
A	ASN59

site_id	MCSA2
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
B	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
B	ASN46
B	ASP48
B	SER50
B	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
B	ASN59

site_id	MCSA3
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
C	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
C	ASN46
C	ASP48
C	SER50
C	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
C	ASN59

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)