4D9B

Pyridoxamine 5' phosphate (PMP) bound form of Salmonella typhimurium D-Cysteine desulfhydrase obtained after co-crystallization with D-cycloserine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016829	molecular_function	lyase activity
A	0019148	molecular_function	D-cysteine desulfhydrase activity
A	0046416	biological_process	D-amino acid metabolic process
B	0003824	molecular_function	catalytic activity
B	0016829	molecular_function	lyase activity
B	0019148	molecular_function	D-cysteine desulfhydrase activity
B	0046416	biological_process	D-amino acid metabolic process
C	0003824	molecular_function	catalytic activity
C	0016829	molecular_function	lyase activity
C	0019148	molecular_function	D-cysteine desulfhydrase activity
C	0046416	biological_process	D-amino acid metabolic process
D	0003824	molecular_function	catalytic activity
D	0016829	molecular_function	lyase activity
D	0019148	molecular_function	D-cysteine desulfhydrase activity
D	0046416	biological_process	D-amino acid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BEN A 401

Chain	Residue
A	TYR30
A	LEU31
A	ILE296
A	HOH716

---

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE PMP A 402

Chain	Residue
A	SER195
A	ALA196
A	GLY197
A	THR198
A	TYR287
A	THR315
A	GLY316
A	GLY317
A	HOH508
A	HOH538
A	HOH702
A	HOH712
A	ASN50
A	LYS51
A	LYS54
A	ASN79
A	GLY194

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 403

Chain	Residue
A	CYS129
A	ASP130

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 404

Chain	Residue
A	SER195
A	SER221
A	ARG222
A	HOH681
A	HOH733

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE PMP B 401

Chain	Residue
B	ASN50
B	LYS51
B	LYS54
B	ASN79
B	GLY194
B	SER195
B	ALA196
B	GLY197
B	THR198
B	TYR287
B	THR315
B	GLY316
B	GLY317
B	HOH510
B	HOH518
B	HOH531
B	HOH656
B	HOH657

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO B 402

Chain	Residue
B	SER195
B	SER221
B	ARG222
B	HOH662

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 403

Chain	Residue
B	ASN265
B	ASP266
B	HOH598
B	HOH684
D	HIS94

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BEN C 401

Chain	Residue
B	TYR30
B	LEU31
C	TYR30
C	LEU31
C	SER300

---

site_id	AC9
Number of Residues	18
Details	BINDING SITE FOR RESIDUE PMP C 402

Chain	Residue
C	ASN50
C	LYS51
C	LYS54
C	ASN79
C	GLY194
C	SER195
C	ALA196
C	GLY197
C	THR198
C	TYR287
C	THR315
C	GLY316
C	GLY317
C	HOH510
C	HOH521
C	HOH604
C	HOH624
C	HOH625

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO C 403

Chain	Residue
C	SER195
C	SER221
C	ARG222
C	HOH617
C	HOH630

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BEN D 401

Chain	Residue
D	TYR30
D	LEU31
D	ILE296

---

site_id	BC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE PMP D 402

Chain	Residue
D	HOH512
D	HOH531
D	HOH645
D	HOH694
D	HOH695
D	ASN50
D	LYS51
D	LYS54
D	ASN79
D	GLY194
D	SER195
D	ALA196
D	GLY197
D	THR198
D	TYR287
D	THR315
D	GLY316
D	GLY317

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO D 403

Chain	Residue
D	SER195
D	SER221
D	ARG222

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255|HAMAP-Rule:MF_01045

Chain	Residue	Details
A	LYS51
B	LYS51
C	LYS51
D	LYS51

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