4D92
Salmonella typhimurium D-Cysteine desulfhydrase soaked with beta-chloro-D-alanine shows pyruvate bound 4 A away from active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016846 | molecular_function | carbon-sulfur lyase activity |
| A | 0019148 | molecular_function | D-cysteine desulfhydrase activity |
| A | 0046416 | biological_process | D-amino acid metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016846 | molecular_function | carbon-sulfur lyase activity |
| B | 0019148 | molecular_function | D-cysteine desulfhydrase activity |
| B | 0046416 | biological_process | D-amino acid metabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016846 | molecular_function | carbon-sulfur lyase activity |
| C | 0019148 | molecular_function | D-cysteine desulfhydrase activity |
| C | 0046416 | biological_process | D-amino acid metabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016846 | molecular_function | carbon-sulfur lyase activity |
| D | 0019148 | molecular_function | D-cysteine desulfhydrase activity |
| D | 0046416 | biological_process | D-amino acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BEN A 401 |
| Chain | Residue |
| A | TYR30 |
| A | LEU31 |
| A | ILE296 |
| A | HOH616 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PYR A 402 |
| Chain | Residue |
| A | SER195 |
| A | SER221 |
| A | ARG222 |
| A | HOH664 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | SER78 |
| A | ASN79 |
| A | HIS80 |
| A | TYR261 |
| A | TYR287 |
| A | HOH531 |
| A | HOH612 |
| A | HOH664 |
| A | LLP51 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BEN B 401 |
| Chain | Residue |
| B | TYR30 |
| B | LEU31 |
| C | TYR30 |
| C | LEU31 |
| C | SER300 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PYR B 402 |
| Chain | Residue |
| B | GLY194 |
| B | SER195 |
| B | SER221 |
| B | ARG222 |
| B | TYR261 |
| B | HOH614 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 403 |
| Chain | Residue |
| B | LLP51 |
| B | SER78 |
| B | ASN79 |
| B | HIS80 |
| B | TYR261 |
| B | TYR287 |
| B | HOH595 |
| B | HOH614 |
| B | HOH644 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PYR C 401 |
| Chain | Residue |
| C | GLY194 |
| C | SER195 |
| C | SER221 |
| C | ARG222 |
| C | TYR261 |
| C | HOH546 |
| C | HOH584 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 C 402 |
| Chain | Residue |
| C | LLP51 |
| C | SER78 |
| C | ASN79 |
| C | HIS80 |
| C | TYR261 |
| C | TYR287 |
| C | HOH527 |
| C | HOH546 |
| C | HOH606 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BEN D 401 |
| Chain | Residue |
| D | TYR30 |
| D | LEU31 |
| D | ILE296 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PYR D 402 |
| Chain | Residue |
| D | VAL158 |
| D | GLY194 |
| D | SER221 |
| D | ARG222 |
| D | TYR261 |
| D | HOH578 |
| D | HOH624 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 D 403 |
| Chain | Residue |
| D | LLP51 |
| D | SER78 |
| D | ASN79 |
| D | HIS80 |
| D | TYR261 |
| D | TYR287 |
| D | HOH578 |
| D | HOH629 |
| D | HOH671 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01045","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
