Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1687 |
| Chain | Residue |
| A | LYS621 |
| A | GLN624 |
| B | ASP519 |
| B | LEU520 |
| B | ASN646 |
| B | HOH2034 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1687 |
| Chain | Residue |
| A | HOH2097 |
| A | SER601 |
| A | ARG668 |
| A | HOH2065 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1688 |
| Chain | Residue |
| B | ARG508 |
| B | GLN512 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1689 |
| Chain | Residue |
| B | HIS480 |
| B | LYS673 |
| B | HOH2036 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 1688 |
| Chain | Residue |
| A | HIS482 |
| A | GLN529 |
| A | HOH2106 |
| A | HOH2107 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGQFGDVHqGiymspenpama.......VAIK |
| Chain | Residue | Details |
| A | ILE428-LYS454 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDIAARNVLV |
| Chain | Residue | Details |
| A | PHE542-VAL554 | |
| site_id | PS00661 |
| Number of Residues | 31 |
| Details | FERM_2 FERM domain signature 2. HrdiaarnvlVSatdCVklgDfgLsrYMeDS |
| Chain | Residue | Details |
| A | HIS544-SER574 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP546 | |
| B | ASP546 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | GLU500 | |
| B | ILE428 | |
| B | LYS454 | |
| B | GLU500 | |
| A | ILE428 | |
| A | LYS454 | |
| Chain | Residue | Details |
| A | TYR576 | |
| B | TYR576 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by SRC => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR577 | |
| B | TYR577 | |
