4D2J
Crystal structure of F16BP Aldolase from Toxoplasma gondii (TgALD1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0051289 | biological_process | protein homotetramerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BME A 1422 |
| Chain | Residue |
| A | SER267 |
| A | ASP269 |
| A | ASP269 |
| A | HIS307 |
| A | CYS311 |
| A | HOH2145 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1417 |
| Chain | Residue |
| A | LYS177 |
| A | HOH2044 |
| A | ASP104 |
| A | SER106 |
| A | THR109 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1418 |
| Chain | Residue |
| A | ARG113 |
| A | GLY373 |
| A | ARG374 |
| A | HOH2138 |
| A | HOH2158 |
| A | HOH2160 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 1419 |
| Chain | Residue |
| A | LYS177 |
| A | VAL178 |
| A | ASP179 |
| A | ARG203 |
| A | TYR207 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1420 |
| Chain | Residue |
| A | THR184 |
| A | SER201 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 1421 |
| Chain | Residue |
| A | ASN121 |
| A | GLU123 |
Functional Information from PROSITE/UniProt
| site_id | PS00158 |
| Number of Residues | 11 |
| Details | ALDOLASE_CLASS_I Fructose-bisphosphate aldolase class-I active site. VlLEGaLLKPN |
| Chain | Residue | Details |
| A | VAL293-ASN303 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"28972169","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Schiff-base intermediate with dihydroxyacetone phosphate","evidences":[{"source":"PubMed","id":"28972169","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5TK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TKC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28972169","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5TK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TKC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TKL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28972169","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5TKC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TKL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P00883","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28972169","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5TK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TKC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28972169","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5TK3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
