4D28

Crystal structure of the kinase domain of CIPK24/SOS2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006468	biological_process	protein phosphorylation
A	0007165	biological_process	signal transduction
A	0009651	biological_process	response to salt stress
A	0009705	cellular_component	plant-type vacuole membrane
A	0106310	molecular_function	protein serine kinase activity
B	0004672	molecular_function	protein kinase activity
B	0004674	molecular_function	protein serine/threonine kinase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0006468	biological_process	protein phosphorylation
B	0007165	biological_process	signal transduction
B	0009651	biological_process	response to salt stress
B	0009705	cellular_component	plant-type vacuole membrane
B	0106310	molecular_function	protein serine kinase activity
C	0004672	molecular_function	protein kinase activity
C	0004674	molecular_function	protein serine/threonine kinase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0006468	biological_process	protein phosphorylation
C	0007165	biological_process	signal transduction
C	0009651	biological_process	response to salt stress
C	0009705	cellular_component	plant-type vacuole membrane
C	0106310	molecular_function	protein serine kinase activity
D	0004672	molecular_function	protein kinase activity
D	0004674	molecular_function	protein serine/threonine kinase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0006468	biological_process	protein phosphorylation
D	0007165	biological_process	signal transduction
D	0009651	biological_process	response to salt stress
D	0009705	cellular_component	plant-type vacuole membrane
D	0106310	molecular_function	protein serine kinase activity

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	33
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGTFAKVKfArntdtgdnvaikimaks.TILK

Chain	Residue	Details
A	ILE17-LYS49

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site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VyHrDLKpeNLLL

Chain	Residue	Details
A	VAL130-LEU142

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027

Chain	Residue	Details
A	ASP134
B	ASP134
C	ASP134
D	ASP134

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
C	ILE17
C	LYS40
D	ILE17
D	LYS40
A	ILE17
A	LYS40
B	ILE17
B	LYS40

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site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q93V58

Chain	Residue	Details
B	SER156
C	SER156
D	SER156
A	SER156

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site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q38997

Chain	Residue	Details
B	ASP168
C	ASP168
D	ASP168
A	ASP168

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