4D1W

A H224Y mutant for VIM-7 from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ZN A 1293

Chain	Residue
A	HIS116
A	HIS118
A	HIS196
A	OCS221
A	ZN1294
A	HOH2118
A	HOH2119

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 1294

Chain	Residue
A	HIS263
A	ZN1293
A	HOH2118
A	HOH2126
A	ASP120
A	OCS221

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Functional Information from PROSITE/UniProt

site_id	PS00743
Number of Residues	20
Details	BETA_LACTAMASE_B_1 Beta-lactamases class B signature 1. IsTHfHDDrvGGvdvlraa.G

Chain	Residue	Details
A	ILE113-GLY133

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"2Y87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y8A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D1T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PDB","id":"2Y87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y8B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D1T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"2Y8A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D1T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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