4D0D

COMPLEX OF A B2 CHICKEN MHC CLASS I MOLECULE AND A 8MER CHICKEN PEPTIDE

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0002376	biological_process	immune system process
B	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
B	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
B	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
B	0002726	biological_process	positive regulation of T cell cytokine production
B	0005198	molecular_function	structural molecule activity
B	0005576	cellular_component	extracellular region
B	0005765	cellular_component	lysosomal membrane
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006955	biological_process	immune response
B	0007611	biological_process	learning or memory
B	0010038	biological_process	response to metal ion
B	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
B	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
B	0023026	molecular_function	MHC class II protein complex binding
B	0031902	cellular_component	late endosome membrane
B	0033572	biological_process	transferrin transport
B	0034756	biological_process	regulation of iron ion transport
B	0034757	biological_process	negative regulation of iron ion transport
B	0042605	molecular_function	peptide antigen binding
B	0042612	cellular_component	MHC class I protein complex
B	0042613	cellular_component	MHC class II protein complex
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0042824	cellular_component	MHC class I peptide loading complex
B	0048260	biological_process	positive regulation of receptor-mediated endocytosis
B	0048261	biological_process	negative regulation of receptor-mediated endocytosis
B	0050680	biological_process	negative regulation of epithelial cell proliferation
B	0050768	biological_process	negative regulation of neurogenesis
B	0050778	biological_process	positive regulation of immune response
B	0050870	biological_process	positive regulation of T cell activation
B	0051289	biological_process	protein homotetramerization
B	0071281	biological_process	cellular response to iron ion
B	0071316	biological_process	cellular response to nicotine
B	1990000	biological_process	amyloid fibril formation
B	1990712	cellular_component	HFE-transferrin receptor complex
B	2000774	biological_process	positive regulation of cellular senescence
B	2000978	biological_process	negative regulation of forebrain neuron differentiation
E	0002376	biological_process	immune system process
E	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
E	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
E	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
E	0002726	biological_process	positive regulation of T cell cytokine production
E	0005198	molecular_function	structural molecule activity
E	0005576	cellular_component	extracellular region
E	0005765	cellular_component	lysosomal membrane
E	0005794	cellular_component	Golgi apparatus
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006955	biological_process	immune response
E	0007611	biological_process	learning or memory
E	0010038	biological_process	response to metal ion
E	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
E	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
E	0023026	molecular_function	MHC class II protein complex binding
E	0031902	cellular_component	late endosome membrane
E	0033572	biological_process	transferrin transport
E	0034756	biological_process	regulation of iron ion transport
E	0034757	biological_process	negative regulation of iron ion transport
E	0042605	molecular_function	peptide antigen binding
E	0042612	cellular_component	MHC class I protein complex
E	0042613	cellular_component	MHC class II protein complex
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0042824	cellular_component	MHC class I peptide loading complex
E	0048260	biological_process	positive regulation of receptor-mediated endocytosis
E	0048261	biological_process	negative regulation of receptor-mediated endocytosis
E	0050680	biological_process	negative regulation of epithelial cell proliferation
E	0050768	biological_process	negative regulation of neurogenesis
E	0050778	biological_process	positive regulation of immune response
E	0050870	biological_process	positive regulation of T cell activation
E	0051289	biological_process	protein homotetramerization
E	0071281	biological_process	cellular response to iron ion
E	0071316	biological_process	cellular response to nicotine
E	1990000	biological_process	amyloid fibril formation
E	1990712	cellular_component	HFE-transferrin receptor complex
E	2000774	biological_process	positive regulation of cellular senescence
E	2000978	biological_process	negative regulation of forebrain neuron differentiation
H	0002376	biological_process	immune system process
H	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
H	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
H	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
H	0002726	biological_process	positive regulation of T cell cytokine production
H	0005198	molecular_function	structural molecule activity
H	0005576	cellular_component	extracellular region
H	0005765	cellular_component	lysosomal membrane
H	0005794	cellular_component	Golgi apparatus
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006955	biological_process	immune response
H	0007611	biological_process	learning or memory
H	0010038	biological_process	response to metal ion
H	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
H	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
H	0023026	molecular_function	MHC class II protein complex binding
H	0031902	cellular_component	late endosome membrane
H	0033572	biological_process	transferrin transport
H	0034756	biological_process	regulation of iron ion transport
H	0034757	biological_process	negative regulation of iron ion transport
H	0042605	molecular_function	peptide antigen binding
H	0042612	cellular_component	MHC class I protein complex
H	0042613	cellular_component	MHC class II protein complex
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0042824	cellular_component	MHC class I peptide loading complex
H	0048260	biological_process	positive regulation of receptor-mediated endocytosis
H	0048261	biological_process	negative regulation of receptor-mediated endocytosis
H	0050680	biological_process	negative regulation of epithelial cell proliferation
H	0050768	biological_process	negative regulation of neurogenesis
H	0050778	biological_process	positive regulation of immune response
H	0050870	biological_process	positive regulation of T cell activation
H	0051289	biological_process	protein homotetramerization
H	0071281	biological_process	cellular response to iron ion
H	0071316	biological_process	cellular response to nicotine
H	1990000	biological_process	amyloid fibril formation
H	1990712	cellular_component	HFE-transferrin receptor complex
H	2000774	biological_process	positive regulation of cellular senescence
H	2000978	biological_process	negative regulation of forebrain neuron differentiation
K	0002376	biological_process	immune system process
K	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
K	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
K	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
K	0002726	biological_process	positive regulation of T cell cytokine production
K	0005198	molecular_function	structural molecule activity
K	0005576	cellular_component	extracellular region
K	0005765	cellular_component	lysosomal membrane
K	0005794	cellular_component	Golgi apparatus
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006955	biological_process	immune response
K	0007611	biological_process	learning or memory
K	0010038	biological_process	response to metal ion
K	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
K	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
K	0023026	molecular_function	MHC class II protein complex binding
K	0031902	cellular_component	late endosome membrane
K	0033572	biological_process	transferrin transport
K	0034756	biological_process	regulation of iron ion transport
K	0034757	biological_process	negative regulation of iron ion transport
K	0042605	molecular_function	peptide antigen binding
K	0042612	cellular_component	MHC class I protein complex
K	0042613	cellular_component	MHC class II protein complex
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0042824	cellular_component	MHC class I peptide loading complex
K	0048260	biological_process	positive regulation of receptor-mediated endocytosis
K	0048261	biological_process	negative regulation of receptor-mediated endocytosis
K	0050680	biological_process	negative regulation of epithelial cell proliferation
K	0050768	biological_process	negative regulation of neurogenesis
K	0050778	biological_process	positive regulation of immune response
K	0050870	biological_process	positive regulation of T cell activation
K	0051289	biological_process	protein homotetramerization
K	0071281	biological_process	cellular response to iron ion
K	0071316	biological_process	cellular response to nicotine
K	1990000	biological_process	amyloid fibril formation
K	1990712	cellular_component	HFE-transferrin receptor complex
K	2000774	biological_process	positive regulation of cellular senescence
K	2000978	biological_process	negative regulation of forebrain neuron differentiation

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YQCRVEH

Chain	Residue	Details
A	TYR253-HIS259
B	TYR77-HIS83

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	352
Details	Domain: {"description":"Ig-like C1-type"}

Chain

Residue

Details

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