4CYD

GlxR bound to cAMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0030552	molecular_function	cAMP binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000166	molecular_function	nucleotide binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0030552	molecular_function	cAMP binding
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription
C	0000166	molecular_function	nucleotide binding
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0030552	molecular_function	cAMP binding
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045893	biological_process	positive regulation of DNA-templated transcription
D	0000166	molecular_function	nucleotide binding
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0005829	cellular_component	cytosol
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0030552	molecular_function	cAMP binding
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE CMP C 1228

Chain	Residue
A	ASN138
C	ARG92
C	THR93
C	SER94
C	ARG133
C	THR137
C	HOH2092
C	PHE41
C	LEU60
C	LEU72
C	PHE81
C	GLY82
C	GLU83
C	LEU84
C	SER85

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE CMP D 1226

Chain	Residue
B	LEU134
B	ASN138
D	PHE41
D	LEU72
D	MET75
D	PHE81
D	GLY82
D	GLU83
D	LEU84
D	SER85
D	ARG92
D	THR93
D	SER94
D	ARG133
D	THR137

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE CMP B 1228

Chain	Residue
B	PHE41
B	LEU60
B	LEU72
B	MET75
B	PHE81
B	GLY82
B	GLU83
B	LEU84
B	SER85
B	ARG92
B	THR93
B	SER94
B	ARG133
B	THR137
B	HOH2053
D	ASN138

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site_id	AC4
Number of Residues	18
Details	BINDING SITE FOR RESIDUE CMP A 1228

Chain	Residue
A	PHE41
A	LEU60
A	LEU72
A	MET75
A	PHE81
A	GLY82
A	GLU83
A	LEU84
A	SER85
A	ARG92
A	THR93
A	SER94
A	ARG133
A	THR137
A	HOH2066
A	HOH2080
C	LEU134
C	ASN138

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1229

Chain	Residue
A	GLU69
A	ASN70
A	GLN185
A	HOH2054
A	HOH2056
A	HOH2110

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 1230

Chain	Residue
A	THR73
A	ILE74
A	GLN159

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